Iyngkaran P. Old, the new, more or less and the conundrum for biomarkers in cardiovascular diseases? World J Clin Cases 2024; 12(28): 6244-6246 [PMID: 39371566 DOI: 10.12998/wjcc.v12.i28.6244]
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Oct 6, 2024; 12(28): 6244-6246 Published online Oct 6, 2024. doi: 10.12998/wjcc.v12.i28.6244
Old, the new, more or less and the conundrum for biomarkers in cardiovascular diseases?
Pupalan Iyngkaran
Pupalan Iyngkaran, Department of Cardiology, Notre Dame University, Werribee 3029, Australia
Pupalan Iyngkaran, Department of Public Health, Torrens Univeristy Australia, Melbourne 3004, Victoria, Australia
Author contributions: Iyngkaran P wrote the paper.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Received: May 29, 2024 Revised: July 20, 2024 Accepted: August 2, 2024 Published online: October 6, 2024 Processing time: 75 Days and 8.6 Hours
Abstract
Biomarkers are critical for diagnostic, monitoring and management of cardiovascular diseases. Opportunities to improve how biomarkers are used are important. This editorial on biomarkers in coronary artery disease provides commentary on the study as well as broad benchmarks on what make ideal biomarkers. Biomarker discovery is difficult and opportunities to expand and improve their use should be encouraged.
Core Tip: Biomarkers are among a few pillars of medical care however caution is raised and encouragement is provided for observations into biomarker studies. Combination of biomarkers are a novel method and may increase the appeal of single biomarkers. Design of experiments to evaluate biomarkers and diseases are as important as the specific biomarkers being tested.
