Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2024; 12(25): 5784-5790
Published online Sep 6, 2024. doi: 10.12998/wjcc.v12.i25.5784
Sinonasal teratocarcinosarcoma involving the nasal cavity, unilateral paranasal sinuses, and intracranial invasion: A case report
Li-Yuan Fu, Mi-Yang Yang, Pei-Yun Ye, Zhao-Chu Wang, Chu-Jie Chen, Hui Li, Shang-Wen Xu
Li-Yuan Fu, Hui Li, Shang-Wen Xu, Department of Radiology, 900th Hospital of Joint Logistics Support Force, Fuzhou 350025, Fujian Province, China
Mi-Yang Yang, Pei-Yun Ye, Zhao-Chu Wang, Chu-Jie Chen, The First Clinical Medical College, Fuzong Teaching Hospital, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, Fujian Province, China
Co-corresponding authors: Hui Li and Shang-Wen Xu.
Author contributions: Fu LY, Ye PY and Yang MY contributed to manuscript writing and editing, and data collection; Wang ZC and Chen CJ contributed to data analysis; Li H and Xu SW contributed to conceptualization and supervision; all authors have read and approved the final manuscript.
Informed consent statement: The patient provided written informed consent.
Conflict-of-interest statement: All authors have no competing interests to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui Li, MD, Doctor, Department of Radiology, 900th Hospital of Joint Logistics Support Force, No. 156 North West Second Ring Road, Fuzhou 350025, Fujian Province, China. 582788441@qq.com
Received: April 2, 2024
Revised: May 22, 2024
Accepted: June 24, 2024
Published online: September 6, 2024
Processing time: 105 Days and 15.5 Hours
Abstract
BACKGROUND

Sinonasal teratocarcinosarcoma (SNTCS) is a rare and highly invasive neoplasm originating from the nasal cavity and sinuses. Typically, it exhibits an invasive behavior towards adjacent structures; however, in exceptional instances, it may infiltrate the intracranial compartment. Due to the tumor's rarity and lack of distinctive features on computed tomography (CT) and magnetic resonance imaging (MRI) images, SNTCS is often misdiagnosed.

CASE SUMMARY

In this study, we present a case of SNTCS in a 56-year-old patient who exhibited unexplained cognitive impairment before admission. CT and MRI scans revealed the presence of a mass in the right nasal cavity, with lesions extending to the right ethmoid sinus and right frontal region. Subsequently, the patient underwent pathological examination for confirmation and received surgical intervention to excise the tumor. The future advancement in our understanding of this disease will significantly contribute to the precise diagnosis and treatment of SNTCS.

CONCLUSION

SNTCS is an exceptionally rare malignant tumor that originates from the nasal cavity and paranasal sinuses, presenting a diagnostic challenge due to its non-specific imaging findings. MRI accurately delineates the location, morphological characteristics, size, internal structure, extent of surrounding involvement, and metabolic information of the lesion. These aspects play a pivotal role in the precise localization and qualitative assessment of SNTCS. Nevertheless, a definitive diagnosis still requires a pathological biopsy.

Keywords: Paranasal sinus; Malignant tumor; Sinonasal teratocarcinosarcoma; Brain invasion; Case report

Core Tip: We present a case report of Sinonasal teratocarcinosarcoma involving the nasal cavity, unilateral paranasal sinuses, and extending into the intracranial region in pathology. Our findings underscore the crucial role of integrating radiology results, clinical manifestations, and pathological biopsy outcomes for accurate diagnosis by clinicians.