Chaudhary PK, Kim S. Shedding light on pancreatic metastasis of clear cell sarcoma: An exceptional journey. World J Clin Cases 2024; 12(25): 5657-5661 [PMID: 39247733 DOI: 10.12998/wjcc.v12.i25.5657]
Corresponding Author of This Article
Soochong Kim, DVM, PhD, Professor, Veterinary Medicine, Chungbuk National University, Chungdae-ro 1, Seowon-Gu, Cheongju 28644, South Korea. skim0026@cbu.ac.kr
Research Domain of This Article
Oncology
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Sep 6, 2024; 12(25): 5657-5661 Published online Sep 6, 2024. doi: 10.12998/wjcc.v12.i25.5657
Shedding light on pancreatic metastasis of clear cell sarcoma: An exceptional journey
Preeti Kumari Chaudhary, Soochong Kim
Preeti Kumari Chaudhary, Soochong Kim, Veterinary Medicine, Chungbuk National University, Cheongju 28644, South Korea
Author contributions: Chaudhary PK and Kim S contributed to this study; Kim S designed the overall concept and outline of the manuscript; Chaudhary PK contributed to the discussion and design of the manuscript; Kim S and Chaudhary PK contributed to the writing and editing of the manuscript, illustrations, and review of the literature.
Supported byNational Research Foundation of Korea, No. NRF-2022R1A2C1003638; and The Basic Research Lab Program through the NRF of Korea Funded by The Ministry of Science and ICT, No. 2022R1A4A1025557.
Conflict-of-interest statement: Preeti Kumari Chaudhary and Soochong Kim have nothing to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Soochong Kim, DVM, PhD, Professor, Veterinary Medicine, Chungbuk National University, Chungdae-ro 1, Seowon-Gu, Cheongju 28644, South Korea. skim0026@cbu.ac.kr
Received: March 26, 2024 Revised: May 9, 2024 Accepted: May 21, 2024 Published online: September 6, 2024 Processing time: 112 Days and 18.7 Hours
Abstract
This editorial comments on the study by Liu et al investigating pancreatic metastasis of clear cell sarcoma (CCS) published in the World Journal of Clinical Cases. CCS is a rare and aggressive melanocytic tumor, that typically arises from tendons and aponeuroses of the limbs, and metastasizes to the lungs, bones, and brain. However, pancreatic metastasis has rarely been reported, presenting unique diagnostic and therapeutic challenges. Elucidating the clinical characteristics, imaging features, prognostic factors, and treatment outcomes of patients with pancreatic CCS metastasis is crucial. Surgery remains an effective management strategy for CCS. However, the high recurrence rate and low effectiveness of traditional adjuvant treatments necessitate a shift towards more personalized and targeted treatment plans. Research is needed to investigate and validate novel therapeutic approaches specifically tailored to the distinct genetic and molecular characteristics of rare malignancies like CCS. Additionally, the development of late metastases after a long disease-free interval is common in CCS patients. Therefore, routine postoperative surveillance for metastasis using computed tomography, magnetic resonance imaging, bone scans, and positron emission tomography scans is crucial. Moving forward, enhanced collaboration, investigation, and creative thinking among scientists, medical professionals, and legislators are essential to gain a deeper understanding of these rare presentations.
Core Tip: Due to the extreme rarity of pancreatic metastasis of clear cell sarcoma (CCS), drawing definitive conclusions about its clinical courses, diagnosis, prognostic factors, and optimal treatment is challenging. Nevertheless, for individuals with a history of CCS, routine postoperative follow-up using computed tomography, magnetic resonance imaging, bone scans, and possibly positron emission tomography scans remains crucial for effective treatment.
