Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2024; 12(20): 4154-4165
Published online Jul 16, 2024. doi: 10.12998/wjcc.v12.i20.4154
Relationship between neonatal respiratory distress syndrome pulmonary ultrasonography and respiratory distress score, oxygenation index, and chest radiography grading
Hai Yang, Li-Jun Gao, Jing Lei, Qiang Li, Liu Cui, Xiao-Hua Li, Wu-Xuan Yin, Sen-Hua Tian
Hai Yang, Jing Lei, Qiang Li, Liu Cui, Xiao-Hua Li, Wu-Xuan Yin, Neonatal Intensive Care Center, Liupanshui Maternal and Child Care Service Center, Liupanshui 553000, Guizhou Province, China
Li-Jun Gao, Ultrasound Function Department, Liupanshui Maternal and Child Care Service Center, Liupanshui 553000, Guizhou Province, China
Sen-Hua Tian, Medical Imaging Department, Liupanshui Maternal and Child Care Service Center, Liupanshui 553000, Guizhou Province, China
Author contributions: Yang H wrote a manuscript; Yang H, Gao LJ, Lei J conceptualized and designed the study; Yang H, Li Q, Cui L, Li XH provided the study materials; Yin WX provided administrative support; Yang H and Tian SH collected and assembled the data; Yang H performed data analysis and interpretation; All authors participated in manuscript writing and approved the final manuscript.
Supported by Guizhou Provincial Science and Technology Department, Technology Achievement Application and Industrialization Plan, Applied Fundamental Research, No. Qianke Synthetic Fruit [2022] 004.
Institutional review board statement: This study was approved by the Ethic Committee of Liupanshui Maternal and Child Care Service Center.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hai Yang, Doctor, Deputy Director, Neonatal Intensive Care Center, Liupanshui Maternal and Child Care Service Center, No. 53 Liangdu Avenue, Zhongshan District, Liupanshui 553000, Guizhou Province, China. haiyang_lps@163.com
Received: April 10, 2024
Revised: May 17, 2024
Accepted: June 3, 2024
Published online: July 16, 2024
Processing time: 81 Days and 18.3 Hours
Abstract
BACKGROUND

Accurate condition assessment is critical for improving the prognosis of neonatal respiratory distress syndrome (RDS), but current assessment methods for RDS pose a cumulative risk of harm to neonates. Thus, a less harmful method for assessing the health of neonates with RDS is needed.

AIM

To analyze the relationships between pulmonary ultrasonography and respiratory distress scores, oxygenation index, and chest X-ray grade of neonatal RDS to identify predictors of neonatal RDS severity.

METHODS

This retrospective study analyzed the medical information of 73 neonates with RDS admitted to the neonatal intensive care unit of Liupanshui Maternal and Child Care Service Center between April and December 2022. The pulmonary ultrasonography score, respiratory distress score, oxygenation index, and chest X-ray grade of each newborn before and after treatment were collected. Spearman correlation analysis was performed to determine the relationships among these values and neonatal RDS severity.

RESULTS

The pulmonary ultrasonography score, respiratory distress score, oxygenation index, and chest X-ray RDS grade of the neonates were significantly lower after treatment than before treatment (P < 0.05). Spearman correlation analysis showed that before and after treatment, the pulmonary ultrasonography score of neonates with RDS was positively correlated with the respiratory distress score, oxygenation index, and chest X-ray grade (ρ = 0.429–0.859, P < 0.05). Receiver operating characteristic curve analysis indicated that pulmonary ultrasonography screening effectively predicted the severity of neonatal RDS (area under the curve = 0.805–1.000, P < 0.05).

CONCLUSION

The pulmonary ultrasonography score was significantly associated with the neonatal RDS score, oxygenation index, and chest X-ray grade. The pulmonary ultrasonography score was an effective predictor of neonatal RDS severity.

Keywords: Neonatal respiratory distress syndrome; Pulmonary ultrasonography; Ultrasonography score; Respiratory distress score; Oxygenation index; Chest X-ray grading

Core Tip: Current diagnostic and therapeutic evaluation methods for neonatal respiratory distress syndrome (RDS) often cause physical harm to neonates. No studies have yet reported the predictive value of pulmonary ultrasonography scores for neonatal RDS. This study evaluated the relationship between changes in the pulmonary ultrasonography score and the respiratory distress score, oxygenation index, and chest X-ray stage before and after treatment of neonatal RDS. Receiver operating characteristic curves showed that the pulmonary ultrasonography score predicted neonatal RDS severity.