Cui LY, Sun CP, Li YY, Liu S. Granulomatous mastitis in a 50-year-old male: A case report and review of literature. World J Clin Cases 2024; 12(2): 451-459 [PMID: 38313639 DOI: 10.12998/wjcc.v12.i2.451]
Corresponding Author of This Article
Chen-Ping Sun, PhD, Chief Physician, Department of Breast Surgery, Longhua Hospital Shanghai University of Traditional Chinese Medicine, No. 725 South Wanping Road, Shanghai 200032, China. scptcm@126.com
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jan 16, 2024; 12(2): 451-459 Published online Jan 16, 2024. doi: 10.12998/wjcc.v12.i2.451
Granulomatous mastitis in a 50-year-old male: A case report and review of literature
Le-Yin Cui, Chen-Ping Sun, Yun-Yuan Li, Sheng Liu
Le-Yin Cui, Chen-Ping Sun, Department of Breast Surgery, Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
Yun-Yuan Li, Department of Pathology, Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
Sheng Liu, Graduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
Author contributions: Cui LY contributed to manuscript writing; Sun CP, Li YY, and Liu S contributed to writing-reviewing and editing; All authors read and approved the final manuscript.
Informed consent statement: Informed consent was obtained from the patient for publication of this case report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chen-Ping Sun, PhD, Chief Physician, Department of Breast Surgery, Longhua Hospital Shanghai University of Traditional Chinese Medicine, No. 725 South Wanping Road, Shanghai 200032, China. scptcm@126.com
Received: November 19, 2023 Peer-review started: November 19, 2023 First decision: November 28, 2023 Revised: December 11, 2023 Accepted: December 21, 2023 Article in press: December 21, 2023 Published online: January 16, 2024 Processing time: 52 Days and 16.6 Hours
Abstract
BACKGROUND
Granulomatous mastitis (GM) an inflammatory disease of the breast that usually affects women of childbearing age, occurs very rarely in males.
CASE SUMMARY
We present a case study of a 50-year-old male patient with GM. The patient developed a breast lump following the cleaning of a previously embedded dirt-filled nipple. While an initial improvement was noted with antibiotic therapy, a recurrence occurred a year later, showing resistance to the previously effective antibiotics. Subsequently, the lesion was excised. The histopathological examination confirmed the diagnosis of GM.
CONCLUSION
GM should be considered a possible diagnosis of male breast masses.
Core Tip: We present the case of a 50-year-old male whose breast lump was excised, confirming the diagnosis of granulomatous mastitis (GM), which occurs in males is very rare. Hormonal imbalances, autoimmunity, and bacterial infections may be associated with GM, for males, hormonal imbalances are most common. A standardized treatment protocol for GM is yet to be established. Male breast cancer and other diseases that cause breast granulomatous should be considered in the differential diagnosis.
