Zhang YZ, Wang YB, Fang JL, Wang YT, Li GF, Liu RR, Shi SJ, Wang CH, Tian YT. Clinical characteristics and analysis of vestibular-evoked myogenic potentials in patients with sudden sensorineural hearing loss in different ages. World J Clin Cases 2024; 12(19): 3760-3766 [PMID: 38994283 DOI: 10.12998/wjcc.v12.i19.3760]
Corresponding Author of This Article
Yong-Tao Tian, MBBS, Associate Chief Physician, Deputy Director, Department of Otolaryngology, Hebei Provincial Eye Hospital, Hebei Provincial Key Laboratory of Ophthalmology, Hebei Provincial Eye Institute, No. 399 Quanbeidong, Xingtai 054001, Hebei Province, China. tianyongtao2022@163.com
Research Domain of This Article
Otorhinolaryngology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Yan-Zhuo Zhang, Ya-Bo Wang, Jing-Lei Fang, Yue-Tang Wang, Gui-Fang Li, Ran-Ran Liu, Shu-Jing Shi, Chun-Hua Wang, Yong-Tao Tian, Department of Otolaryngology, Hebei Provincial Eye Hospital, Hebei Provincial Key Laboratory of Ophthalmology, Hebei Provincial Eye Institute, Xingtai 054001, Hebei Province, China
Author contributions: Zhang YZ, Wang YB and Fang JL collected the patients’ information; Zhang YZ reviewed the literature, and drafted this manuscript; Tian YT and Wang CH analyzed the cases, and checked all works and words and approved the final version for submission.; Li GF, Liu RR, Shi SJ and Wang YT helped to analyze and interpret audiology and vestibular function data. All authors have read and approve the final manuscript.
Supported bythe Innovative Program of Hebei Provincial Eye Hospital, No. 2023ZZ107.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of the Hebei Eye Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors declared no conflict of interest existing in this paper.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong-Tao Tian, MBBS, Associate Chief Physician, Deputy Director, Department of Otolaryngology, Hebei Provincial Eye Hospital, Hebei Provincial Key Laboratory of Ophthalmology, Hebei Provincial Eye Institute, No. 399 Quanbeidong, Xingtai 054001, Hebei Province, China. tianyongtao2022@163.com
Received: March 6, 2024 Revised: April 22, 2024 Accepted: May 10, 2024 Published online: July 6, 2024 Processing time: 115 Days and 3.7 Hours
Abstract
BACKGROUND
Numerous studies have found that patients experiencing sudden sensorineural hearing loss (SSHL), with or without accompanying vertigo, often show impaired vestibular function. However, there is a dearth of studies analyzing vestibular-evoked myogenic potentials (VEMPs) in SSHL patients across various age groups.
AIM
To investigate vestibular condition in SSHL patients across various age demographics.
METHODS
Clinical data of 84 SSHL patients were investigated retrospectively. Audiometry, cervical vestibular evoked myogenic potentials (c-VEMPs), and ocular vestibular evoked myogenic potentials (o-VEMPs) were conducted on these patients. Parameters assessed included the latencies of P1 and N1 waves, as well as the amplitudes of P1–N1 waves. Moreover, the study evaluated the influence of factors such as sex, affected side, configuration of hearing loss, and presence of accompanying vertigo.
RESULTS
Among the 84 SSHL patients, no significant differences were observed among the three groups in terms of gender, affected side, and the presence or absence of vertigo. Group II (aged 41–60 years) had the highest number of SSHL cases. The rates of absent o-VEMPs in the affected ears were 20.83%, 31.58%, and 22.72% for the three age groups, respectively, with no statistically significant difference among them. The rates of absent c-VEMPs in the affected ears were 8.3%, 34.21%, and 18.18% for the three age groups, respectively, with significant differences. In the unaffected ears, there were differences observed in the extraction rates of o-VEMPs in the unaffected ears among the age groups. In the three age groups, no significant differences were noted in the three age groups in the latencies of P1 and N1 waves or in the amplitude of N1–P1 waves for c-VEMPs and o-VEMPs, either on the affected side or on the unaffected side, across the three age groups.
CONCLUSION
The extraction rate of VEMPs is more valuable than parameters. Regardless of the presence of vertigo, vestibular organs are involved in SSHL. Notably, SSHL patients aged 41–60 appear more susceptible to damage to the inferior vestibular nerve and saccule.
Core Tip: Patients with sudden sensorineural hearing loss (SSHL), whether accompanied by vertigo or not, often show impaired vestibular function. By observing the extraction rate and various parameter indicators of vestibular-evoked myogenic potentials (VEMPs) in different age groups of SSHL patients, we found that the extraction rate of VEMPs is more valuable, and the Group II (aged 41–60 years) with the highest number of SSHL cases, and patients aged 41-60 years had the highest number of profound hearing loss and the lowest cervical-VEMPs extraction rate in affected ear. The results indicates that SSHL aged 41-60 years old patients are more susceptible to damage to the inferior vestibular nerve and saccule.
