Dai JH, Qian F, Chen L, Xu SL, Feng XF, Wu HB, Chen Y, Peng ZH, Yu PW, Peng GY. Novel combined endoscopic and laparoscopic surgery for advanced T2 gastric cancer: Two case reports. World J Clin Cases 2023; 11(9): 2029-2035 [PMID: 36998943 DOI: 10.12998/wjcc.v11.i9.2029]
Corresponding Author of This Article
Gui-Yong Peng, MD, Chief Physician, Department of Gastroenterology, Southwest Hospital, The Third Military Medical University, No. 30 Gaotan Yanzheng Street, Shapingba District, Chongqing 400038, China. pgy63@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Mar 26, 2023; 11(9): 2029-2035 Published online Mar 26, 2023. doi: 10.12998/wjcc.v11.i9.2029
Novel combined endoscopic and laparoscopic surgery for advanced T2 gastric cancer: Two case reports
Jian-Hua Dai, Feng Qian, Lei Chen, Sen-Lin Xu, Xiao-Feng Feng, Hong-Bo Wu, Yao Chen, Zhi-Hong Peng, Pei-Wu Yu, Gui-Yong Peng
Jian-Hua Dai, Lei Chen, Xiao-Feng Feng, Hong-Bo Wu, Yao Chen, Zhi-Hong Peng, Gui-Yong Peng, Department of Gastroenterology, Southwest Hospital, The Third Military Medical University, Chongqing 400038, China
Feng Qian, Pei-Wu Yu, Department of General Surgery, Southwest Hospital, The Third Military Medical University, Chongqing 400038, China
Sen-Lin Xu, Department of Pathology, Southwest Hospital, The Third Military Medical University, Chongqing 400038, China
Author contributions: Dai JH, Qian F and Chen L contributed equally to this work, and they were involved in the patient treatment and postoperative management; Xu SL provided pathological data and corresponding analysis; Feng XF, Wu HB, Chen Y, Peng ZH and Yu PW analyzed the cases and postoperative management; Peng GY designed the research study, performed endoscopic treatments on patients and wrote the manuscript; All authors have read and approved the final manuscript.
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gui-Yong Peng, MD, Chief Physician, Department of Gastroenterology, Southwest Hospital, The Third Military Medical University, No. 30 Gaotan Yanzheng Street, Shapingba District, Chongqing 400038, China. pgy63@163.com
Received: December 1, 2022 Peer-review started: December 1, 2022 First decision: January 2, 2023 Revised: January 14, 2023 Accepted: February 22, 2023 Article in press: February 22, 2023 Published online: March 26, 2023 Processing time: 105 Days and 21.2 Hours
Abstract
BACKGROUND
The standard treatment for advanced T2 gastric cancer (GC) is laparoscopic or surgical gastrectomy (either partial or total) and D2 lymphadenectomy. A novel combined endoscopic and laparoscopic surgery (NCELS) has recently been proposed as a better option for T2 GC. Here we describe two case studies demonstrating the efficacy and safety of NCELS.
CASE SUMMARY
Two T2 GC cases were both resected by endoscopic submucosal dissection and full-thickness resection and laparoscopic lymph nodes dissection. This method has the advantage of being more precise and minimally invasive compared to current methods. The treatment of these 2 patients was safe and effective with no complications. These cases were followed up for nearly 4 years without recurrence or metastasis.
CONCLUSION
This novel method provides a minimally invasive treatment option for T2 GC, and its potential indications, effectiveness and safety needs to be further evaluated in controlled studies.
Core Tip: We propose a new method of combining endoscopic local lesion resection and laparoscopic lymph node dissection for 2 cases of advanced T2 gastric cancer (GC). This new method has the advantages of precision and being minimally invasive with similar outcomes as surgical resection. It is a novel method providing a minimally invasive treatment option for T2 GC.
