Published online Oct 6, 2023. doi: 10.12998/wjcc.v11.i28.6902
Peer-review started: July 11, 2023
First decision: August 24, 2023
Revised: August 30, 2023
Accepted: September 14, 2023
Article in press: September 14, 2023
Published online: October 6, 2023
Processing time: 76 Days and 8.7 Hours
Testicular mixed germ cell tumors (TMGCTs) are rare malignant tumors that are more common in men aged 20–40 years. TMGCTs comprise two or more types of germ cell tumors that primarily affect the testis. Their onset is undetectable; thus, early diagnosis is challenging. However, early recognition and diagnosis substantially improve patient prognosis.
We evaluated a rare case of TMGCT in a male patient presenting with recurrent fever and left supraclavicular lymphadenectasis instead of testicular enlargement and pain, which may easily lead to misdiagnosis. We report the clinical signs and symptoms, histopathological characteristics, and immunohistochemical results of this case of malignant TMGCT.
Our case, which was typical with multiple components, along with a literature review, may serve as a basis for early diagnosis.
Core Tip: We evaluated a rare case of testicular mixed germ cell tumor (TMGCT) in a male patient presenting with recurrent fever and left supraclavicular lymphadenectasis, instead of testicular enlargement and pain, which may easily lead to misdiagnosis. We report the clinical signs and symptoms, histopathological characteristics, and immunohistochemistry findings of this case of malignant TMGCT. Our case, which presented multiple components typical of TMGCT, along with a literature review, may serve as a basis for the early recognition and diagnosis of this disease.