Chen Q, Niu YL. Successful treatment of a case of COVID-19 pneumonia following kidney transplantation using paxlovid and tocilizumab. World J Clin Cases 2023; 11(25): 6012-6018 [PMID: 37727489 DOI: 10.12998/wjcc.v11.i25.6012]
Corresponding Author of This Article
Qian Chen, Doctor, Chief Physician, Professor, Researcher, Department of Organ Transplantation, Affiliated Hospital of Guizhou Medical University, No. 28 Gui Medical Street, Beijing Road, Yunyan District, Guiyang 550000, Guizhou Province, China. chenqian1056659393@163.com
Research Domain of This Article
Biology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Sep 6, 2023; 11(25): 6012-6018 Published online Sep 6, 2023. doi: 10.12998/wjcc.v11.i25.6012
Successful treatment of a case of COVID-19 pneumonia following kidney transplantation using paxlovid and tocilizumab
Qian Chen, Yu-Lin Niu
Qian Chen, Yu-Lin Niu, Department of Organ Transplantation, Affiliated Hospital of Guizhou Medical University, Guiyang 550000, Guizhou Province, China
Author contributions: Chen Q and Niu YL wrote and collated the manuscript; Niu YL reviewed the manuscript; All authors contributing to the article and approving the submitted version.
Supported byGuiyang Science and Technology Program, No. 2019-9-1-39.
Informed consent statement: Informed written consent was obtained from the patient and her parents for the publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qian Chen, Doctor, Chief Physician, Professor, Researcher, Department of Organ Transplantation, Affiliated Hospital of Guizhou Medical University, No. 28 Gui Medical Street, Beijing Road, Yunyan District, Guiyang 550000, Guizhou Province, China. chenqian1056659393@163.com
Received: July 6, 2023 Peer-review started: July 6, 2023 First decision: July 18, 2023 Revised: July 26, 2023 Accepted: August 3, 2023 Article in press: August 3, 2023 Published online: September 6, 2023 Processing time: 56 Days and 20.7 Hours
Abstract
BACKGROUND
Since its initial detection in 2019, coronavirus disease 2019 (COVID-19) pneumonia has rapidly spread throughout the world in a global pandemic. However, reports of COVID-19 pneumonia among patients following kidney transplantation have been limited and no uniform treatment guidelines for these patients have yet to be established.
CASE SUMMARY
Here, we report the case of a 39-year-old patient recovering from kidney transplantation who contracted perioperative COVID-19 pneumonia that was successfully controlled with oral paxlovid and a single intravenous drip infusion of tocilizumab following the discontinuation of immunosuppressive drugs.
CONCLUSION
Given the rapid spread of severe acute respiratory syndrome coronavirus 2 infections, clinicians should be aware of the potential for more cases of COVID-19 among patients following kidney transplantation and be familiar with appropriate treatment options and likely clinical outcomes.
Core Tip: Here, we report the case of a 39-year-old patient recovering from kidney transplantation who contracted perioperative coronavirus disease 2019 (COVID-19) pneumonia that was successfully controlled with oral paxlovid and a single intravenous drip infusion of tocilizumab following the discontinuation of immunosuppressive drugs. Given the rapid spread of severe acute respiratory syndrome coronavirus 2 infections, clinicians should be aware of the potential for more cases of COVID-19 among patients following kindey transplantation and be familiar with appropriate treatment options and likely clinical outcomes.
