Published online Jul 26, 2023. doi: 10.12998/wjcc.v11.i21.5187
Peer-review started: May 24, 2023
First decision: June 13, 2023
Revised: June 26, 2023
Accepted: July 7, 2023
Article in press: July 7, 2023
Published online: July 26, 2023
Processing time: 63 Days and 18.1 Hours
Brucellosis is one of the most common zoonotic infectious diseases in the world, with approximately 500000 new cases of human brucellosis diagnosed each year. Brucellosis can simulate various multi-system diseases, presenting atypical symptoms. Very few brucellosis cases with pancytopenia accompanied by a se
A 64-year-old woman presented with dizziness and fatigue, accompanied by pancytopenia and severe hearing loss. Brucella melitensis was identified on blood culture. Anti-infective therapy with rifampicin (900 mg/d) and doxycycline (100 mg twice a day) was prescribed for 4 mo along with ceftriaxone 2 g/d for 1 mo. The patient showed a good response to antibiotic therapy. Her blood counts re
Brucellosis should be considered in the differential diagnosis of patients pre
Core Tip: Brucellosis is a zoonotic disease that has recently shown a resurgence across the world. Brucellosis can affect multiple systems in the human body and the clinical manifestations may be atypical, making the diagnosis more difficult. In this article, we report a rare case of brucellosis presenting with pancytopenia and severe hearing loss. A series of tests ruled out a blood disorder, Brucella melitensis was identified on blood culture. The patient recovered well without sequelae after receiving anti-infective medication with rifampicin, doxycycline, and ceftriaxone. This report may help improve the understanding of brucellosis among clinicians in non-endemic areas.