Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 6, 2023; 11(13): 3092-3098
Published online May 6, 2023. doi: 10.12998/wjcc.v11.i13.3092
Eosinophilic fasciitis difficult to differentiate from scleroderma: A case report
Tian-Yi Lan, Zi-Han Wang, Wei-Ping Kong, Jin-Ping Wang, Nan Zhang, Di-Er Jin, Jing Luo, Qing-Wen Tao, Ze-Ran Yan
Tian-Yi Lan, Zi-Han Wang, Graduate College, Beijing University of Chinese Medicine, Beijing 100029, China
Wei-Ping Kong, Jin-Ping Wang, Nan Zhang, Di-Er Jin, Jing Luo, Qing-Wen Tao, Ze-Ran Yan, Traditional Chinese Medicine Department of Rheumatism, China-Japan Friendship Hospital, Beijing 100029, China
Author contributions: Yan ZR conceived and designed the study; Lan TY collected the data and wrote the manuscript; Wang ZH performed the patient follow-up; all authors read and approved the final manuscript.
Supported by National Natural Science Foundation of China, No. 81704050; and National High Level Hospital Clinical Research Funding, No. 2022-NHLHCRF-LX-02-0103 and No. 2022-NHLHCRF-LX-02-0104.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ze-Ran Yan, PhD, Doctor, Traditional Chinese Medicine Department of Rheumatism, China-Japan Friendship Hospital, No. 2 Yinghua Street East, Beijing 100029, China. yanzeran@126.com
Received: January 8, 2023
Peer-review started: January 8, 2023
First decision: February 20, 2023
Revised: March 2, 2023
Accepted: March 27, 2023
Article in press: March 27, 2023
Published online: May 6, 2023
Processing time: 107 Days and 6 Hours
Abstract
BACKGROUND

Eosinophilic fasciitis (EF) is a rare connective tissue disease that can cause swelling and sclerosis of the extremities, and special attention is needed to differentiate EF from systemic sclerosis. Misdiagnosis or omission markedly delays treatment of EF, and severe skin sclerosis in advanced stages can cause joint contracture and tendon retraction, worsening the patient's prognosis and quality of life.

CASE SUMMARY

We report a case of EF in a young woman diagnosed by tissue biopsy, confirming the difficulty of differential diagnosis with scleroderma.

CONCLUSION

Focusing on skin manifestations, completing tissue biopsy and radiography can help diagnose EF effectively. Clinicians should enhance their understanding of the differences between EF and scleroderma, and early diagnosis and standardized treatment can improve the prognosis of patients with EF.

Keywords: Eosinophilic fasciitis; Scleroderma; Biopsy; Diagnose; Prognosis; Case report

Core Tip: Eosinophilic fasciitis (EF) is a rare connective tissue disease and special attention should be paid to differentiating it from scleroderma. Misdiagnosis or omission markedly delays the appropriate treatment of EF, worsening the prognosis and reducing the quality of life of the patient. We report a case of EF in a young woman diagnosed by tissue biopsy, confirming the difficulty of differential diagnosis with scleroderma. Clinicians should be more aware of EF, and early diagnosis and standardized treatment may improve the prognosis of patients.