Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 6, 2023; 11(13): 3010-3016
Published online May 6, 2023. doi: 10.12998/wjcc.v11.i13.3010
Bilateral malignant glaucoma with bullous keratopathy: A case report
Ya-Bin Ma, Ya-Long Dang
Ya-Bin Ma, Ya-Long Dang, Department of Ophthalmology, Sanmenxia Central Hospital, Sanmenxia 472000, Henan Province, China
Author contributions: Dang YL contributed to conception of the study; Dang YL performed the surgery; Ma YB and Dang YL contributed significantly to analysis and manuscript preparation; all authors have read and approved the final manuscript.
Supported by The Central Guiding Local Science & Technology Projects, No. Z20221341047; The Major Scientific and Technological Project of Sanmenxia 2022, No. 2022001007
Informed consent statement: Written informed consent was obtained from the patient for the publication of this case report.
Conflict-of-interest statement: All authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ya-Long Dang, MD, PhD, Associate Chief Physician, President, Surgeon, Department of Ophthalmology, Sanmenxia Central Hospital, Wenhua Street, Sanmenxia 472000, Henan Province, China. dangyalong@126.com
Received: October 7, 2022
Peer-review started: October 7, 2022
First decision: December 26, 2022
Revised: January 22, 2023
Accepted: March 31, 2023
Article in press: March 31, 2023
Published online: May 6, 2023
Processing time: 199 Days and 19.7 Hours
Abstract
BACKGROUND

Malignant glaucoma, caused by aqueous misdirection, is a challenging post-surgical complication presented with normal/high intraocular pressure and shallowing of the central and peripheral anterior chambers. Its incidence is about 0.6%-4.0%. It can be secondary to filtering surgeries, laser iridotomy, and cataract surgery. Short axial length and a history of angle closure glaucoma are its main risk factors. Here, we report a bilateral malignant glaucoma with bullous keratopathy in the patient’s left eye.

CASE SUMMARY

We present a case of bilateral malignant glaucoma. The cause of malignant glaucoma for each eye of this patient was different. Hence, the management strategy and selection of surgical methods were also different. However, the normal anterior chamber was ultimately maintained, and maximum visual function was preserved. Even though the left eye received multiple surgeries and corneal endothelial decompensation occurred, the formation of a retroendothelial fibrous membrane partially compensated for the function of the corneal endothelium.

CONCLUSION

The formation of a retroendothelial fibrous membrane partially compensated for the function of the corneal endothelium.

Keywords: Malignant glaucoma; Corneal epithelial cell; Lens epithelial cell; Bullous keratopathy; Retroendothelial fibrous membrane; Case report

Core Tip: Malignant glaucoma, caused by aqueous misdirection, is a challenging post-surgical complication presented with normal/high intraocular pressure and shallowing of the central and peripheral anterior chambers. Its incidence is about 0.6%-4.0%. It can be secondary to filtering surgeries, laser iridotomy, and cataract surgery. Short axial length and a history of angle closure glaucoma are its main risk factors. Here, we report bilateral malignant glaucoma with bullous keratopathy in the patient’s left eye. Interestingly, the best corrected visual acuity of the left eye improved to 20/70, and bullous keratopathy was relieved after the migration and implant of lens epithelial cells into the corneal endothelium.