Wang YL, Zhang HW, Lin F. Computed tomography combined with gastroscopy for assessment of pancreatic segmental portal hypertension. World J Clin Cases 2022; 10(24): 8568-8577 [PMID: 36157801 DOI: 10.12998/wjcc.v10.i24.8568]
Corresponding Author of This Article
Han-Wen Zhang, MD, Doctor, Department of Radiology, The First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People’s Hospital, No. 3002 Sungangxi Road, Shenzhen 518035, Guangdong Province, China. zhwstarcraft@outlook.com
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Radiology, Nuclear Medicine & Medical Imaging
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Aug 26, 2022 (publication date) through Mar 2, 2026
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World Journal of Clinical Cases
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Wang YL, Zhang HW, Lin F. Computed tomography combined with gastroscopy for assessment of pancreatic segmental portal hypertension. World J Clin Cases 2022; 10(24): 8568-8577 [PMID: 36157801 DOI: 10.12998/wjcc.v10.i24.8568]
World J Clin Cases. Aug 26, 2022; 10(24): 8568-8577 Published online Aug 26, 2022. doi: 10.12998/wjcc.v10.i24.8568
Computed tomography combined with gastroscopy for assessment of pancreatic segmental portal hypertension
Yu-Li Wang, Han-Wen Zhang, Fan Lin
Yu-Li Wang, Han-Wen Zhang, Fan Lin, Department of Radiology, The First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People’s Hospital, Shenzhen 518035, Guangdong Province, China
Author contributions: Zhang HW contributed to the conception of the study; Lin F performed the data analyses and wrote the manuscript; Wang YL helped perform the analysis with constructive discussions.
Supported byShenzhen Science and Technology Plan Project, No. JCYJ20180228163333734.
Institutional review board statement: This study was approved by the local ethics committee (Ethics Committee of Shenzhen Second People's Hospital), No. 20211108009.
Clinical trial registration statement: This study is registered at Ethics Committee of Shenzhen Second People's Hospital. This study is registered at Chinese Clinical Trial Registry. The registration identification number is ChiCTR2100049175.
Informed consent statement: This study included completely anonymous data, and the ethics committee agreed to waive the patient's right of informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All data used in this study are included in the article.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Corresponding author: Han-Wen Zhang, MD, Doctor, Department of Radiology, The First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People’s Hospital, No. 3002 Sungangxi Road, Shenzhen 518035, Guangdong Province, China. zhwstarcraft@outlook.com
Received: February 26, 2022 Peer-review started: February 26, 2022 First decision: May 11, 2022 Revised: May 13, 2022 Accepted: July 22, 2022 Article in press: July 22, 2022 Published online: August 26, 2022 Processing time: 170 Days and 12.3 Hours
Abstract
BACKGROUND
Pancreatic segmental portal hypertension (PSPH) is the only type of portal hypertension that can be completely cured. However, it can easily cause varicose veins in the esophagus and stomach and hemorrhage in the digestive tract.
AIM
To explore the application of computed tomography (CT) to examine the characteristics of PSPH and assess the risk level.
METHODS
This was a retrospective analysis of CT images of 22 patients diagnosed with PSPH at our center. Spearman correlation analysis was performed using the range of esophageal and gastric varices (measured by the vertical gastric wall), the ratio of the width of the splenic portal vein to that of the compression site (S/C ratio), the degree of splenomegaly, and the stage determined by gastroscopy. This study examined whether patients experienced gastrointestinal bleeding within 2 wk and combined CT and gastroscopy to explore the connection between bleeding and CT findings.
RESULTS
The range of esophageal and gastric varices showed the best correlation in the diagnosis of PSPH (P < 0.001), and the S/C ratio (P = 0.007) was correlated with the degree of splenomegaly (P = 0.021) and PSPH (P < 0.05). This study revealed that male patients were more likely than females to progress to grade 2 or grade 3 as determined by gastroscopy. CT demonstrated excellent performance, with an area under the curve of 0.879.
CONCLUSION
CT can be used to effectively analyze the imaging signs of PSPH, and CT combined with gastroscopy can effectively predict the risk level of gastrointestinal bleeding.
Core Tip: This is a detailed clinical imaging study (computed tomography, CT) of pancreatic segmental portal hypertension (PSPH), the only curable form of portal hypertension. CT is of great significance in the diagnosis and treatment of PSPH.
