Published online Aug 16, 2022. doi: 10.12998/wjcc.v10.i23.8428
Peer-review started: March 30, 2022
First decision: June 19, 2022
Revised: June 24, 2022
Accepted: July 16, 2022
Article in press: July 16, 2022
Published online: August 16, 2022
Processing time: 124 Days and 0.5 Hours
Intranasal sufentanil combined with intranasal dexmedetomidine exhibited an estimated sedation success probability as high as 94.9%, higher satisfaction scores, and only minor adverse events during endoscopic ultrasonography (EUS). This is a promising method for EUS sedation that does not require the presence of an anesthesiologist.
Core Tip: Endoscopic ultrasonography (EUS) requires moderate-to-deep sedation due to a prolonged procedure time and a larger and stiffer probe. Propofol-based sedation is the predominant method used in such cases for rapid onset and improved sedation with rapid full recovery. However, there are still restrictions regarding the administration of propofol in the absence of an anesthesiologist. The combination of intranasal sufentanil and intranasal dexmedetomidine exhibited an estimated sedation success probability, higher satisfaction scores, and minor adverse events, thus highlighting a promising method for EUS sedation in the absence of an anesthesiologist.