Published online Jul 6, 2022. doi: 10.12998/wjcc.v10.i19.6543
Peer-review started: September 14, 2021
First decision: September 29, 2021
Revised: November 2, 2021
Accepted: May 5, 2022
Article in press: May 5, 2022
Published online: July 6, 2022
Processing time: 283 Days and 4.2 Hours
Esophageal granular cell tumor (eGCT) is a relatively rare, usually benign neoplasm of the neuroectoderm. It is derived from Schwann cells. Clinical symptoms of this disease are non-specific. However, the most common presenting symptom is dysphagia, which is mostly misdiagnosed as esophageal polyps under gastroscopy, yet it has a 2% chance of forming cancers. We report the case of a 52-year-old woman with solitary eGCT, then analysed retrospectivelyanalyze the clinical features and elucidate on the reduction of misdiagnosis and missed diagnosis.
A 52-year-old woman was diagnosed with “esophageal granulossoma” after esophagoscopy, which was mistaken for eGCT.
eGCT diagnosis depends on characteristic pathomorphologies and detection of the S-100 protein. Endoscopic mucosal resection is the preferred therapeutic method.
Core Tip: Esophageal granular cell tumor is a relatively rare, usually benign neoplasm of the neuroectoderm. It is derived from Schwann cells. Clinical symptoms of this disease are non-specific. However, the most common presenting symptom is dysphagia, which is mostly misdiagnosed as esophageal polyps under gastroscopy, yet it has a 2% chance of forming cancers. In this report, clinical features are analyzed to facilitate the reduction of misdiagnosis and missed diagnosis.