He J, Mu Y, Che BW, Liu M, Zhang WJ, Xu SH, Tang KF. Comprehensive treatment for primary right renal diffuse large B-cell lymphoma with a renal vein tumor thrombus: A case report. World J Clin Cases 2022; 10(16): 5352-5358 [PMID: 35812668 DOI: 10.12998/wjcc.v10.i16.5352]
Corresponding Author of This Article
Kai-Fa Tang, MD, PhD, Chief Doctor, Professor, Department of Urology, The Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Street, Guiyang 550004, Guizhou Province, China. tangkaifa@gmc.edu.cn
Research Domain of This Article
Urology & Nephrology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jun 6, 2022; 10(16): 5352-5358 Published online Jun 6, 2022. doi: 10.12998/wjcc.v10.i16.5352
Comprehensive treatment for primary right renal diffuse large B-cell lymphoma with a renal vein tumor thrombus: A case report
Jun He, Yi Mu, Bang-Wei Che, Miao Liu, Wen-Jun Zhang, Sheng-Han Xu, Kai-Fa Tang
Jun He, Yi Mu, Bang-Wei Che, Miao Liu, Wen-Jun Zhang, Sheng-Han Xu, Kai-Fa Tang, Department of Urology, The Affiliated Hospital of Guizhou Medical University, Guiyang 550004, Guizhou Province, China
Kai-Fa Tang, Institute of Medical Science, Guizhou Medical University, Guiyang 550004, Guizhou Province, China
Author contributions: He J performed the case study and wrote the manuscript; Mu Y and Liu M conducted the clinical examination of the patient; Che BW, Zhang WJ and Xu SH edited the manuscript; Tang KF performed the operation and supervised the work; all authors provided final approval of the version to be submitted.
Supported byFoundation of Health Commission of Guizhou Province of China, No. gzwkj2021-211.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kai-Fa Tang, MD, PhD, Chief Doctor, Professor, Department of Urology, The Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Street, Guiyang 550004, Guizhou Province, China. tangkaifa@gmc.edu.cn
Received: July 24, 2021 Peer-review started: July 24, 2021 First decision: December 17, 2021 Revised: December 21, 2021 Accepted: April 21, 2022 Article in press: April 21, 2022 Published online: June 6, 2022 Processing time: 313 Days and 2 Hours
Abstract
BACKGROUND
Renal involvement in lymphoma is commonly associated with widespread nodal or extranodal lymphoma. Primary renal diffuse large B-cell lymphoma is an extremely rare extranodal lymphoma, accounting for fewer than 1% of all renal masses. Interestingly, the patient in this study had a renal vein tumor thrombus that was observed after laparoscopic radical nephrectomy.
CASE SUMMARY
We report the case of a 56-year-old female patient with primary renal lymphoma and a renal vein tumor thrombus whose first symptom was right pain in the back and gross hematuria. Histopathology revealed primary renal diffuse large B-cell lymphoma. The patient received 8 standard cycles of rituximab with cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy after surgery, and no obvious signs of recurrence were observed during the one-year follow-up.
CONCLUSION
We evaluated comprehensive treatment of primary renal diffuse large B-cell lymphoma and multidisciplinary management of this malignancy.
Core Tip: Primary renal diffuse large B-cell lymphoma is an extremely rare extranodal lymphoma. This case also had a simultaneous right renal vein tumor thrombus whose first symptom was right waist pain and gross hematuria. Clinical features and treatment options may contribute to good prognoses. When surgery is combined with chemotherapy, the overall survival is relatively better.
