Published online May 26, 2022. doi: 10.12998/wjcc.v10.i15.5111
Peer-review started: January 6, 2022
First decision: February 21, 2022
Revised: March 1, 2022
Accepted: March 27, 2022
Article in press: March 27, 2022
Published online: May 26, 2022
Processing time: 138 Days and 10.5 Hours
Acute pulmonary embolism (APE) is a rare and potentially life-threatening condition, even with early detection and prompt management. Intraoperative APE required specific ways for detecting since classic symptoms of APE in the awake patient could not be observed or self-reported by the patient under general anesthesia.
A 44-year-old man with a history of hepatic cell carcinoma was admitted for radical nephrectomy and tumor thrombectomy due to a newly found kidney tumor with inferior vena cava (IVC) tumor thrombus. APE that occurred during tumor thrombectomy with hypercapnia and desaturation. The capnography combined with the transesophageal echocardiography (TEE) provided a crucial differential diagnosis during the operation. The patient was continuously managed with aggressive intravenous fluid resuscitation and blood transfusion under continuous cardiac output monitoring to maintain hemodynamic stability. He completed the surgery under stable hemodynamics and was extubated after percutaneous mechanical thrombectomy by a certified cardiologist. There were no significant symptoms and signs or obvious discomfort in the patient’s self-report during visits to the general ward.
Under general anesthesia for IVC tumor thrombus surgery, a sudden decrease in end-tidal carbon dioxide is the initial indicator of APE, which occurs before hemodynamic changes. When intraoperative APE is suspected, TEE is useful in the diagnosis and monitoring before computer tomography pulmonary angiogram. Timely clinical impression and supportive treatment and intervention should be conducted to obtain a better prognosis.
Core Tip: Intraoperative acute pulmonary embolism (APE) is a potentially life-threatening condition, while early detection with prompt management may help improve prognosis. An acute decrease in end-tidal carbon dioxide is an early sign indicating APE. When intraoperative APE is suspected, transesophageal echocardiography is useful in the diagnosis and monitoring before computer tomography pulmonary angiogram. Besides rapid diagnosis, further management and supportive treatment should also be considered to save the patient’s life.