Published online May 26, 2022. doi: 10.12998/wjcc.v10.i15.4935
Peer-review started: September 27, 2021
First decision: January 11, 2022
Revised: February 21, 2022
Accepted: April 3, 2022
Article in press: April 3, 2022
Published online: May 26, 2022
Processing time: 239 Days and 12.9 Hours
Wernekink commissural syndrome (WCS) is a distinct midbrain syndrome that involves the caudal tegmentum of the midbrain and selectively damages the Wernekink commissure involved in the decussation of the superior cerebellar peduncle in midbrain. The aim of the study was to explore the clinical manifestations, imaging characteristics, and differential diagnosis of WCS in midbrain infarction to provide reference for clinicians in the diagnosis of WCS.
The clinical data of 4 patients with WCS with midbrain infarction were analyzed retrospectively. WCS is a rare syndrome that can be diagnosed based on its characteristic symptoms and imaging findings of magnetic resonance imaging.
Clinicians should look for this syndrome in cases of bilateral cerebellar dysfunction and eye movement disorders.
Core Tip: The aim of the study was to explore the clinical manifestations, imaging characteristics, and differential diagnosis of Wernekink commissural syndrome (WCS) in midbrain infarction and to provide reference for the clinicians in the diagnosis of WCS. WCS is a rare syndrome that can be diagnosed based on its characteristic symptoms and imaging findings of magnetic resonance imaging. Clinicians should look for this syndrome in cases of bilateral cerebellar dysfunction and eye movement disorders.