Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.345
Peer-review started: August 13, 2021
First decision: September 5, 2021
Revised: September 16, 2021
Accepted: November 25, 2021
Article in press: November 25, 2021
Published online: January 7, 2022
Processing time: 139 Days and 5.2 Hours
Breast cancer patients have a high skin metastasis rate. However, reports on treatment of cutaneous metastases of breast cancer are scarce.
We report the treatment process for one breast cancer case with bone, lung, and skin metastases. The patient was a 43-year-old woman with advanced breast cancer and skin metastasis. She underwent pathological diagnosis by needle biopsy to guide the treatment. When the disease progressed, a new pathological diagnosis was determined by needle biopsy to guide the treatment. The patient received chemotherapy, endocrine therapy, and photodynamic dynamic therapy, followed by sonodynamic therapy.
Repeated puncture should be performed for advanced breast cancer with skin metastasis, in order to obtain the pathology and directly determine diagnosis when the disease progresses. The treatment should focus on controlling the systemic metastasis, rather than the local disease.
Core Tip: Breast cancer as the most prevalent neoplasm among female individuals, is also the main source of cutaneous metastasis other than melanoma. Breast cancer skin metastasis presents at the terminal stage of advanced cancer, and local treatment can be used to control locally metastatic lesions. As for cases involving a huge breast mass with ulceration or local lesion, radiation therapy is a useful tool for symptomatic control. Advanced breast cancer with skin metastasis can be repeatedly punctured to obtain pathology to directly inform diagnosis when the disease progresses.