Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.249
Peer-review started: February 1, 2021
First decision: July 16, 2021
Revised: July 26, 2021
Accepted: November 24, 2021
Article in press: November 24, 2021
Published online: January 7, 2022
Processing time: 331 Days and 15 Hours
Accurate delineation of the target area for patients with hypopharyngeal cancer is the key to achieving an ideal radiotherapy effect. Since computed tomography (CT) alone can no longer meet the treatment needs, fusing CT images with magnetic resonance imaging (MRI) or positron emission tomography (PET) images can overcome the disadvantages of CT. Herein, we present a clinical case of hypopharyngeal cancer to delineate the tumor volume using combined MRI-CT and PET-CT fusion images to examine if they could accurately cover the tumor volume.
A 67-year-old male patient with hypopharyngeal carcinoma could not tolerate chemotherapy and surgery due to complicated health issues such as diabetic nephropathy and other underlying diseases. After multidisciplinary consultations, clinicians eventually agreed to undergo radiotherapy to control the progression of his tumor. He was examined by CT, MRI, and 18-fluorodeoxyglucose-PET for treatment planning, and CT images were fused with PET and MRI images while delineating tumor volume.
The image fusion of MRI-CT and PET-CT has both advantages and disadvantages. Compared with CT images alone, the combination of MRI-CT and PET-CT fusion images can precisely cover the gross tumor volume in hypopharyngeal carcinoma and avoid overestimation or incomplete coverage of tumor volume.
Core Tip: Magnetic resonance imaging (MRI) and computed tomography (CT) image fusion or positron emission tomography (PET) and CT image fusion is often used to delineate the target areas of hypopharyngeal cancer. Both have their advantages and disadvantages. We report an elderly patient with hypopharyngeal cancer who needed radiotherapy. By combining MRI-CT and PET-CT fusion images to delineate the gross tumor volume, the radiation dose can be maximized, the coverage range is more accurate, and the surrounding normal organs and tissues can be effectively spared.