Integrating serum ferritin and neutrophil-to-lymphocyte ratio with Sequential Organ Failure Assessment score improves mortality prediction in sepsis

Figure 1 Workflow of patient enrollment. ICU: Intensive care unit.

Figure 2 KMunicate style plot. A: Ferritin quartiles; B: Neutrophil-to-lymphocyte ratio quartiles. NLR: Neutrophil-to-lymphocyte ratio; ICU: Intensive care unit.

Figure 3 Area under the receiver operating characteristic curve curves showing apparent and corrected area under the receiver operating characteristic curve. AUC: Area under the curve; AUROC: Area under the receiver operating characteristic curve; SOFA: Sequential Organ Failure Assessment.

Figure 4 Calibration plot for Sequential Organ Failure Assessment model, Sequential Organ Failure Assessment plus ferritin model, and Sequential Organ Failure Assessment plus neutrophil-to-lymphocyte ratio plus ferritin model. A: This figure indicates that calibration is near the ideal line with mean absolute error of 0.011 in a cohort of 1.954 patients with 1000 resamples; B: This figure indicates that calibration is near the ideal line with mean absolute error of 0.008 in a cohort of 1.954 patients with 1000 resamples; C: This figure indicates that calibration is near the ideal line but slightly deviated in high-risk patients with mean absolute error of 0.021 in a cohort of 1.954 patients with 1000 resamples. NLR: Neutrophil-to-lymphocyte ratio; SOFA: Sequential Organ Failure Assessment.