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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Methodol. Mar 20, 2026; 16(1): 112686
Published online Mar 20, 2026. doi: 10.5662/wjm.v16.i1.112686
Published online Mar 20, 2026. doi: 10.5662/wjm.v16.i1.112686
Effects of rosuvastatin treatment and other statins on burn wound healing
Alexandra G Marneri, Christina Mouratidou, Serafeim-Chrysovalantis Kotoulas, Intensive Care Unit, Hippokration General Hospital, Thessaloniki 54642, Greece
Efstathios T Pavlidis, Kalliopi E Stavrati, Theodoros E Pavlidis, The Second Department of Propaedeutic Surgery, Hippokration General Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki 54642, Greece
Konstantinos D Ballas, The Fifth Department of Surgery, Hippokration Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki 54642, Greece
Co-corresponding authors: Efstathios T Pavlidis and Theodoros E Pavlidis.
Author contributions: Marneri AG, Pavlidis ET, and Stavrati KE designed research and analyzed data; Pavlidis ET and Pavlidis TE have played important and indispensable roles in the experimental design, data interpretation and manuscript preparation as the co-corresponding authors; Mouratidou C and Kotoulas SC performed research, contributed new analytic tools, evaluated data and review the paper; Βallas KD and Pavlidis TE analyzed data review and approved the paper; all of the authors read and approved the final version of the manuscript to be published.
Conflict-of-interest statement: The authors declared no potential conflicts of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Theodoros E Pavlidis, MD, PhD, Professor Emeritus, The Second De
Received: August 4, 2025
Revised: August 16, 2025
Accepted: September 18, 2025
Published online: March 20, 2026
Processing time: 191 Days and 20.1 Hours
Revised: August 16, 2025
Accepted: September 18, 2025
Published online: March 20, 2026
Processing time: 191 Days and 20.1 Hours
Core Tip
Core Tip: Burn injuries represent a significant global public health concern and can result in severe complications. The correlation between delays in the wound-healing process of burn injuries with increased mortality rates has led numerous investigators to devise novel therapeutic approaches aimed at accelerating the recovery of burn wounds. Statins, in addition to lowering cholesterol, enhance wound healing, particularly in burn wounds. The statins used include lovastatin, sim