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World J Methodol. Mar 20, 2026; 16(1): 107488
Published online Mar 20, 2026. doi: 10.5662/wjm.v16.i1.107488
Artificial intelligence in mobile health applications: A comprehensive review of its role in diabetes care
Wen-Jie Li, Lin-Ze Li
Wen-Jie Li, School of Art Design and Media, Guangzhou Xinhua University, Guangzhou 510520, Guangdong Province, China
Lin-Ze Li, School of the Arts, Universiti Sains Malaysia, Penang 11800, Malaysia
Author contributions: Li WJ was mainly responsible for drafting and structuring the manuscript, including the initial composition and integration of content, and played a key role in refining and editing the manuscript; Li LZ completed the systematic collection and organization of relevant literature, as well as revision of the manuscript, to ensure its academic rigor and coherence; and all authors thoroughly reviewed and endorsed the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Lin-Ze Li, PhD, School of the Arts, Universiti Sains Malaysia, Chancellory, Level 1, Building E42, Penang 11800, Malaysia. lilinze@student.usm.my
Received: March 25, 2025
Revised: May 10, 2025
Accepted: August 5, 2025
Published online: March 20, 2026
Processing time: 323 Days and 1.2 Hours
Abstract

This review explores the integration of artificial intelligence (AI) in mobile health applications for diabetes care. It focuses on key AI methodologies - machine learning, deep learning, and natural language processing - and their roles in glucose monitoring, personalized self-management, risk prediction, and clinical decision support. Drawing on recent literature (2018-2024), the study outlines the benefits of AI in improving accuracy, engagement, and precision in diabetes treatment. Challenges such as data privacy, algorithmic bias, and regulatory barriers are also examined. A new section discusses when AI technologies may become burdensome, especially in low-resource settings or for users with limited digital literacy. The review concludes with directions for enhancing model explainability and integrating AI with wearable and Internet of Things devices, emphasizing the need for ethical and equitable implementation in future diabetes management strategies.

Keywords: Artificial intelligence; Mobile health; Diabetes management; Predictive analytics; Clinical decision support; Personalized self-management

Core Tip: This review highlights the transformative role of artificial intelligence in mobile health applications for diabetes care. It synthesizes recent advances in machine learning, deep learning, and natural language processing, examining their use in glucose monitoring, personalized interventions, and clinical decision support. The review also discusses ethical challenges, data privacy, and situations where artificial intelligence may become burdensome. By bridging technology and practice, this study offers insights into building more equitable, efficient, and patient-centered diabetes management systems.