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World J Nephrol. Mar 25, 2026; 15(1): 113212
Published online Mar 25, 2026. doi: 10.5527/wjn.v15.i1.113212
Association of chronic kidney disease with in-hospital mortality of cardiogenic shock patients undergoing veno-arterial extracorporeal membrane oxygenation
Mounika Reddy Vadiyala, Jeffy Varghese, Giorgi Chilingarashvili, Vibhor Ahluwalia, Sakshi Sharma, Syed Mohammad Moosi Raza, Harsh Sura, Adhvithi Pingili, Rupak Desai
Mounika Reddy Vadiyala, Jeffy Varghese, Department of Internal Medicine, Maimonides Medical Center, Brooklyn, NY 11219, United States
Giorgi Chilingarashvili, Vibhor Ahluwalia, Department of Internal Medicine, Nazareth Hospital, Philadelphia, PA 19152, United States
Sakshi Sharma, Department of Pediatric Anesthesia, Washington University School of Medicine, St Louis, MO 63130, United States
Syed Mohammad Moosi Raza, Department of Internal Medicine, Cape Fear Valley Health Hospital, Methodist University, Fayetteville, NC 28304, United States
Harsh Sura, Department of Pulmonary and Critical Care Medicine, Rush University, Chicago, IL 60612, United States
Adhvithi Pingili, Department of Cardiology, Kansas University of Medical Center, Kansas City, KS 66160, United States
Rupak Desai, Outcomes Research Researcher, Atlanta, GA 30033, United States
Author contributions: Vadiyala MR and Varghese J performed data curation, validation, investigation and interpretation; Vadiyala MR, Varghese J, Chilingarashvili G, Ahluwalia V, Sura H, and Sharma S wrote the manuscript; Vadiyala MR, Ahluwalia V, Sharma S, Raza SMM, Pingili A, Desai R were involved in visualization; Vadiyala MR and Desai R reviewed and edited the manuscript; Desai R was involved in conceptualization, methodology, formal analysis and supervision and guidance. All authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Corresponding author: Rupak Desai, MD, MBBS, Senior Researcher, Outcomes Research Researcher, Scottdale, Atlanta, GA 30033, United States. drrupakdesai@gmail.com
Received: August 19, 2025
Revised: November 10, 2025
Accepted: January 19, 2026
Published online: March 25, 2026
Processing time: 207 Days and 15 Hours
Core Tip

Core Tip: The impact of chronic kidney disease on in-hospital mortality of patients receiving veno-arterial extracorporeal membrane oxygenation for cardiogenic shock is assessed through our study. It emphasizes how chronic kidney disease, which is frequently present in critically ill patients as a pre-existing comorbidity, may be a significant prognostic factor influencing clinical outcomes. The study offers new insights by examining this relationship across diverse populations and clinical settings. The study provides new insights into patient selection, risk assessment, and future directions for veno-arterial extracorporeal membrane oxygenation care in this patient population.