Transplant-free survival in dengue-associated acute liver failure: Current evidence and future directions

Figure 1 Methodology. A flow diagram outlining the literature search and study selection process for this review. A total of 360 articles were retrieved from the PubMed database using keywords related to the dengue, acute liver failure, and transplant-free survival. After screening, 63 studies were included in the final review. ALF: Acute liver failure; WHO: World Health Organization; RCA: Reference Citation Analysis.

Figure 2 Number of dengue cases from year 2010 to 2025. Data were obtained from the World Health Organization[16].

Figure 3 Number of dengue induced deaths from year 2010 to 2025. Data were obtained from the World Health Organization[16].

Figure 4 Map showing number of dengue cases in 2025. Data were obtained from the World Health Organization[16]. The image created with mapchat.net.

Figure 5 Map showing number of deaths due to dengue infections in 2025. Data were obtained from the World Health Organization[16]. The image created with mapchat.net.

Figure 6 Risk factors and their incidence, and incidence of dengue induced complications. DENV: Dengue virus; NSAID: Non-steroidal anti-inflammatory drug; DSS: Dengue shock syndrome; DHF: Dengue hemorrhagic fever; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; CBC: Complete blood count.

Figure 7 Mechanism of liver injury in patients with dengue infection. ROS: Reactive oxygen species.