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World J Virol. Jun 25, 2026; 15(2): 117858
Published online Jun 25, 2026. doi: 10.5501/wjv.v15.i2.117858
Published online Jun 25, 2026. doi: 10.5501/wjv.v15.i2.117858
Letter to the Editor: Physical functioning as a neglected determinant of antiviral adherence in chronic hepatitis B
Xiao-Feng Huang, The Third Clinical Medical College, Xinjiang Medical University, Urumqi 830017, Xinjiang Uygur Autonomous Region, China
Jing-Qi Zeng, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China
Author contributions: Huang XF drafted the manuscript; Zeng JQ critically revised the manuscript and supervised the work; both authors approved the final version of the manuscript.
AI contribution statement: During the process of writing the manuscript, an AI-assisted language tool was used. This AI tool was only employed for language polishing, grammar correction, and improving the readability and expression effectiveness of the article. It was not used to generate original scientific content, data, references, or conclusions.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Jing-Qi Zeng, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Yangguang South Street, Liangxiang Higher Education Park, Fangshan District, Beijing 102488, China. zjingqi@163.com
Received: December 18, 2025
Revised: January 6, 2026
Accepted: January 26, 2026
Published online: June 25, 2026
Processing time: 182 Days and 24 Hours
Revised: January 6, 2026
Accepted: January 26, 2026
Published online: June 25, 2026
Processing time: 182 Days and 24 Hours
Core Tip
Core Tip: New evidence indicates that physical functioning plays a more important role than affordability in shaping medication adherence among people with chronic hepatitis B. Addressing residual fatigue and related symptoms may be critical for sustaining long-term antiviral therapy.