BPG is committed to discovery and dissemination of knowledge
Case Report Open Access
Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Virol. Jun 25, 2026; 15(2): 117106
Published online Jun 25, 2026. doi: 10.5501/wjv.v15.i2.117106
Emergency robotic-assisted repair in an elderly patient with strangulated hernia and active influenza A infection: A case report
Kyriacos Evangelou, Department of Medicine, National and Kapodistrian University of Athens, Athens 11527, Greece
Kyriacos Evangelou, Thalia Petropoulou, Department of General Surgery, Aretaieion University Hospital, Athens 11528, Greece
Andreas Polydorou, Thalia Petropoulou, Department of Minimally Invasive Colon and Rectal Surgery, The Euroclinic Hospital of Athens, Athens 11521, Greece
ORCID number: Kyriacos Evangelou (0000-0002-3240-5366); Andreas Polydorou (0000-0001-6165-3492); Thalia Petropoulou (0000-0001-5486-5905).
Author contributions: Evangelou K, Polydorou A, and Petropoulou T contributed to manuscript writing and editing; Polydorou A and Petropoulou T contributed to data collection; Evangelou K contributed to data analysis; Polydorou A and Petropoulou T contributed to conceptualization and supervision; all authors have read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare no conflicts of interest associated with the present manuscript.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Kyriacos Evangelou, MD, Department of Medicine, National and Kapodistrian University of Athens, 75 Mikras Asias Street, Athens 11527, Greece. evangeloukyriacos@gmail.com
Received: November 28, 2025
Revised: February 11, 2026
Accepted: March 24, 2026
Published online: June 25, 2026
Processing time: 202 Days and 16.9 Hours

Abstract
BACKGROUND

Emergency repair of strangulated hernias in elderly patients with active respiratory viral infections is high risk and poorly described. This case reports the first emergency robotic-assisted transabdominal preperitoneal (r-TAPP) repair performed in an elderly patient with active influenza A infection, highlighting surgical and infection-control adaptations enabling safe outcomes.

CASE SUMMARY

An 80-year-old male with significant comorbidities presented with a strangulated left inguinal hernia and confirmed influenza A (H3N2) infection, associated with abdominal pain, bowel obstruction, and mild hypoxaemia. Emergency robotic r-TAPP repair was performed using targeted modifications, including ultra-low-pressure pneumoperitoneum, ultra-low particulate air filtration, and lung-protective ventilation. Operative time was 85 minutes with minimal blood loss. The patient was extubated immediately postoperatively, experienced no complications, and was discharged on postoperative day two. Antiviral therapy was continued without respiratory deterioration or nosocomial transmission.

CONCLUSION

Emergency robotic-assisted repair of strangulated hernia can be safely performed in selected elderly patients with active respiratory viral infection when appropriate surgical, anaesthetic, and infection-control strategies are applied.

Key Words: Influenza A; H3N2; Respiratory tract infections; Inguinal hernia; Acute care surgery; Robotic surgical procedures; Case report

Core Tip: This case demonstrates the safe and feasible use of emergency robotic-assisted surgery for strangulated hernia transabdominal preperitoneal repair in an elderly patient with an active influenza A (H3N2) infection. Key modifications in surgical approach, anaesthesia, and infection control (such as ultra-low-pressure pneumoperitoneum, ultra-low particulate air filtration, and lung-protective ventilation) were implemented to reduce postoperative complications. The case provides valuable insights into managing high-risk surgical patients with active respiratory viral infections, offering a model for future emergency robotic-assisted surgeries during potential future viral pandemics.



INTRODUCTION

Robotic platforms have revolutionized the field of elective surgery by reducing incisions, postoperative pain, and hospital stays thanks to their high-definition 3D visualization and enhanced dexterity, that enable surgeons to perform complex manoeuvres with greater accuracy[1]. Robotic-assisted surgery is gradually gaining ground in emergency settings as well[2], offering much-needed faster intervention times, improved precision, and more stability for navigating the challenges of distorted anatomy, suturing in inflamed tissue, and reducing blood loss[3].

Although the 2021 World Society of Emergency Surgery position paper reported that robotic-assisted surgery can be considered feasible and safe in selected haemodynamically stable patients[4], very little is known about its safety and feasibility in patients with active respiratory system viral infections. Literature is limited to scarce case reports, and most such surgeries had been performed during the coronavirus disease 2019 (COVID-19) pandemic[5]. Concerns that respiratory viral particles could be actively released and transmitted to healthcare professionals during abdominal robotic-assisted surgery, or that viral aerosolisation might be exacerbated by carbon dioxide insufflation and cautery, are valid when managing affected patients[5-8].

Active influenza A infection has been associated with increased perioperative risk, including higher rates of postoperative pulmonary complications, prolonged ventilation, and increased morbidity, particularly in elderly patients with comorbidities. Reported postoperative pulmonary complication rates in patients undergoing surgery with active respiratory viral infection range between approximately 20%-40%, with significantly higher risk in those with chronic lung disease[9]. Robotic-assisted surgery may offer distinct advantages in such scenarios by combining precision and safety with physiological benefits such as low-pressure pneumoperitoneum, minimal postoperative pain, and improved respiratory recovery[10].

In this high-risk context, robotic surgery may offer advantages over conventional laparoscopy beyond general ergonomic benefits. These include the ability to maintain effective surgical exposure at lower pneumoperitoneum pressures, enhanced precision in strangulated tissue dissection, reduced operative stress in confined anatomical planes, and improved surgeon–patient distancing during prolonged emergency procedures. Importantly, the closed robotic system facilitates controlled smoke evacuation with ultra-low particulate air (ULPA) filtration, potentially reducing aerosolized viral exposure to operating room staff.

Herein, we present the case of an 80-year-old male with multiple comorbidities who successfully underwent emergency robotic-assisted transabdominal preperitoneal (r-TAPP) repair for a strangulated inguinal hernia amidst an active polymerase chain reaction (PCR)-confirmed influenza A infection. We highlight key modifications in surgical, anaesthetic, and infection-control protocols to emphasize the need for tailored robotic strategies in managing high-risk surgical patients with active viral infections in emergency settings, and to contribute to pandemic preparedness.

CASE PRESENTATION
Chief complaints

An 80-year-old male presented to the emergency department with severe abdominal pain, abdominal distension (meteorism), nausea, and inability to pass gas or stool. He also reported cough, shortness of breath, fever, and decreased appetite.

History of present illness

The patient experienced an abrupt onset of left inguinal abdominal pain approximately 6 hours prior to presentation. This was accompanied by a sudden onset of nausea, meteorism, and the absence of gas and stool passage within a few hours. The cough began five days prior to admission and had been dry and non-productive from the outset. Over the past 48 hours, mild exertional dyspnoea and decreased appetite additionally developed. The patient also reported fever exceeding 38 °C; however, he was unable to recall the exact time of measurement or the precise temperature.

History of past illness

The patient denied any similar symptom combination in the past; his present complaints were experienced for the first time.

Personal and family history

The patient’s personal history includes arterial hypertension (first diagnosed 15 years ago), diabetes mellitus (first diagnosed ten years ago), mild chronic obstructive pulmonary disease (COPD; diagnosed 7 years ago), and osteopenia (diagnosed 2 years ago). He is classified as class I obese (body mass index 31.0 kg/m2) and American Society of Anesthesiologists score IV, with no history of abdominal surgery.

His medication history includes 5 mg amlodipine twice daily per orally (os), 500 mg metformin tablets twice daily per os, 90 μg albuterol (inhaler) as needed for COPD, 1000 IU vitamin D3 once daily per os, and 200 mg ibuprofen per os taken over the counter for occasional joint pain. He confirmed he was using no herbal supplements or nonprescription medications other than ibuprofen.

He receives an annual dose of influenza vaccine (last dose in October 2024) and has received the pneumococcal polysaccharide vaccine (PPSV23) in October 2019. His vaccination against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was completed with a two-dose Pfizer-BioNTech series vaccine in May 2021, and a booster dose in October 2022.

No adverse drug or food reactions were recorded in his history. He reports a well-balanced (Mediterranean) diet, consisting of regular meals, with no restrictions related to his diabetes or hypertension. He had been instructed to limit his sodium intake and monitor his carbohydrate intake, which he admitted he had omitted.

He is a former smoker of 40 pack-years (quit 5 years ago), consumes a glass of wine occasionally, and denies any history of drug use. He is a retired civil engineer and lives independently with family support for daily activities.

The patient’s family history is unremarkable, besides hypertension (both parents) and coronary heart disease (father). There is no known family history of gastrointestinal cancers or hernias.

Physical examination

Upon presentation, the patient appeared as an elderly white male, 1.70 m in height and weighing 89.5 kg. He was alert but in moderate distress due to pain. His complexion was flushed, without signs of acute respiratory distress.

Vital signs demonstrated elevated blood pressure (17.4/11.4 kPa), regular pulse of 88 bpm, respiratory rate of 20 breaths/minute, temperature of 38.3 °C, and mild hypoxaemia with an oxygen saturation of 88% on room air before supplemental oxygen administration.

Cardiovascular examination revealed normal heart sounds without murmurs or gallops; peripheral pulses were palpable and symmetric, and capillary refill time was < 2 seconds.

Respiratory examination showed clear breath sounds bilaterally, with mild expiratory wheezing, more pronounced in the lower lobes. There were no rales or signs of consolidation, although mild use of accessory muscles suggested increased work of breathing.

Abdominal examination revealed distension with a prominent, tender, and irreducible left inguinal lump measuring approximately 6 cm × 5 cm, consistent with a strangulated inguinal hernia. The overlying skin appeared erythematous and warm to touch. Localized tenderness was present in the left lower quadrant and over the inguinal region. The patient rated the pain as 7/10 on the Visual Analogue Scale. Percussion elicited tympanic notes, consistent with gaseous bowel distension, and bowel sounds were hypoactive.

Laboratory examinations

The preoperative laboratory findings are summarized in Table 1. Mild leucocytosis and C-reactive protein (CRP) elevation suggested an infection or inflammation. All other panels, including coagulation parameters, were normal, except for mild hypoxaemia indicated by a PaO2 of 9.7 kPa on arterial blood gas analysis.

Table 1 Preoperative laboratory findings upon presentation.
Panel
Result
Lab range
CBC
WBC (cells/μL)135004500-11000
Hb (g/dL)14.213.0-17.0
PLT (cells/μL)220000150000-400000
Inflammatory markers
CRP (mg/dL)62.0< 10.0
Renal function
sCr (mg/dL)1.00.6-1.2
BUN (mg/dL)18.17.0-20.0
GFR (mL/minute/1.73 m2)83.0> 60.0
Liver function tests
AST (U/L)25.00-40.0
ALT (U/L)22.00-40.0
Total bilirubin (mg/dL)0.70.1-1.2
ABG
pH7.427.35-7.45
PaCO2 (kPa)5.04.7-6.0
PaO2 (kPa)9.710.0-13.3
HCO3 (mEq/L)23.022.0-28.0
Virology
Influenza A PCR Ct (cycles)20

PCR was positive for the influenza A (H3N2) strain, with a cycle threshold value of 20 cycles, consistent with a high viral load and active infection.

Imaging examinations

Initially, a chest X-ray was performed considering the possibility of a respiratory tract infection. The lower lung fields demonstrated mild peribronchial thickening bilaterally, with no evidence of pneumonia or parenchymal consolidation. The cardiac silhouette was normal in size, with no free subdiaphragmatic air observed.

Considering the patient’s age, comorbidities, and normal renal function, an intravenous contrast-enhanced computed tomography (CT) scan followed to visualize potential free fluid or gas within the bowel wall and delineate the contents, location, and size of the hernia sac for surgical planning. CT confirmed the presence of a left inguinal hernia with the incarcerated sigmoid colon within the hernia sac. Mild bowel wall oedema was noted, with no signs of ischaemia or perforation, nor free intraperitoneal air or fluid.

FINAL DIAGNOSIS

The patient was diagnosed with a strangulated left inguinal hernia containing the incarcerated sigmoid colon concurrently with active influenza A (H3N2)-induced bronchitis.

TREATMENT

Given the patient’s advanced age, multiple comorbidities, and active respiratory infection, the management strategy was determined after rapid interdisciplinary consultation between the attending surgeon, anaesthesiologist, and infectious disease specialist. The Influenza A infection was immediately addressed with oseltamivir 75 mg twice daily, continued for a total of seven days.

Despite the presence of active influenza A infection, immediate surgical intervention was mandated due to clinical and radiological features consistent with hernia strangulation, including bowel obstruction and risk of ischemia. Delaying surgery in this context carries a well-established risk of bowel necrosis, perforation, sepsis, and mortality, which outweighs the risks associated with proceeding during active viral infection. Non-operative management was therefore not considered a safe alternative, and surgery was performed under enhanced anaesthetic and infection-control precautions. To minimize surgical trauma and postoperative complications such as wound infection, pneumonia, and delayed recovery, a minimally invasive approach was selected.

The operating surgeon was a board-certified minimally invasive and robotic colorectal consultant with formal fellowship training and experience exceeding 250 robotic-assisted procedures, including numerous emergency cases. The team included two experienced bedside assistants (each with > 150 robotic cases), a scrub nurse specialized in robotic instrumentation, and an anaesthesiologist trained in prolonged minimally invasive procedures. The institution has performed more than 150 robotic-assisted operations, ensuring full team familiarity with the platform and workflow.

Preoperatively and considering the patient’s mild hypoxaemia, history of COPD, and respiratory reserve compromise due to the infection, the anaesthesia team developed an adapted lung-protective ventilation strategy to reduce the risk of acute respiratory distress syndrome (ARDS), exacerbation of existing pulmonary conditions, and postoperative respiratory complications such as atelectasis and pulmonary oedema. To minimize the risk of viral aerosolisation, a rapid sequence induction was performed with cricoid pressure to prevent aspiration.

A strategy of 6 mL/kg of ideal body weight for tidal volume was used, in line with ARDS network recommendations[11], to minimize the risk of ventilator-induced lung injury (VILI). A plateau pressure of < 2.45 kPa was maintained during mechanical ventilation to minimize the risk of barotrauma or VILI, while moderate positive end-expiratory pressure (0.7 kPa) was applied to prevent atelectasis, improve oxygenation, and ensure lung recruitment. Oxygen therapy was optimized to maintain oxygen saturation by pulse oximeter (SpO2) levels > 95%, using fraction of inspired oxygen adjustments as necessary.

Surgical staff were required to wear personal protective equipment including N95 filtering facepiece respirators. All team members in direct contact with the patient wore face shields and surgical hoods in addition to the standard gloves and gowns. Robotic surgical instruments were sterilized using high-temperature autoclaving and ethylene oxide sterilization, while a closed-loop insufflation system with ULPA filters was utilized for gas flow and ventilation during surgery.

For the r-TAPP approach, the patient was positioned in minimal Trendelenburg position to avoid exacerbating his hypoxaemia. An ultra-low-pressure pneumoperitoneum (ULPP) of 1.0 kPa was deliberately selected instead of the standard 1.6-2.0 kPa to minimize respiratory compromise while preserving adequate exposure through robotic articulation and stable 3D visualization.

The da Vinci Xi robotic system was used, with an 8 mm supraumbilical camera port and three 8 mm instrument ports, one in the left lower quadrant and two in the right lower quadrant.

Upon entry and exploration of the abdominal cavity, the incarcerated left inguinal hernia was identified with the sigmoid colon trapped within its sac. The bowel was assessed for viability, and there were no signs of ischaemia or necrosis. The hernia sac was dissected, and the incarcerated bowel was reduced (Figure 1).

Figure 1
Figure 1 Incarcerated inguinal hernia with sigmoid colon content. A: Incarcerated sigmoid colon within the inguinal hernia sac, with a thin, stretched peritoneal band at the neck of the defect; B: Close-up of the herniated sigmoid colon at the inguinal defect, with the constricting peritoneal band and surrounding adhesions exposed; C: Sigmoid colon after release from the hernia sac, showing reactive hyperaemia but intact serosa; D: Final view of the inguinal defect after reduction of the sigmoid colon, with protruding preperitoneal/hernia fat and the divided peritoneal band.

Following successful bowel reduction, the preperitoneal space was dissected to expose the inguinal region. In the absence of bowel necrosis, perforation, or enteric spillage, the operative field was not considered contaminated, and standard mesh-based repair was therefore performed using a non-absorbable polypropylene mesh (Prolene) to cover the hernia defect. The mesh was placed preperitoneally to cover the inguinal ring tension-free and was secured in place using sutures (Figure 2). The peritoneum was closed over the mesh, and the surgical site was inspected for haemostasis.

Figure 2
Figure 2 Preperitoneal mesh placement. A macroporous non-absorbable polypropylene mesh (Prolene) is spread flat over the hernia defect to cover the inguinal ring tension-free while a suture is placed through it.

The robotic instruments were carefully removed from the operative field under direct visualisation via the camera. Before closure, it was ensured that the preperitoneal space was fully clear of any residual tissue or foreign bodies.

The peritoneal layer was closed using absorbable monofilament sutures (Monocryl 1-0) in a continuous running technique. The 8 mm supraumbilical port site was closed using a subcuticular absorbable suture (Monocryl), size 2-0 for deep closure and 4-0 for the superficial layer. A single-layer closure was performed with a running subcuticular stitch. The three 8 mm port sites were closed with absorbable sutures (Vicryl 3-0) using a simple interrupted technique. In addition to suturing, 3M Steri-Strips were applied over the port sites.

OUTCOME AND FOLLOW-UP

The surgery lasted a total of 85 minutes and the estimated blood loss was minimal (20 mL). No intraoperative complications were recorded.

The patient was extubated immediately after surgery and in the operating room. He was then transferred to the high-dependency unit (HDU) for observation, where oxygen therapy was administered at 2 L/minute via nasal cannula to maintain SpO2 > 95%. A chest X-ray was performed postoperatively to assess for pneumothorax or infection worsening, with none detected.

It was decided that the patient would remain in the HDU until discharge, as part of the infection control measures. Oseltamivir, amlodipine, metformin, and vitamin D3 were continued during his hospitalization.

On the first postoperative day, his laboratory results showcased a white blood cell count of 12500 cells/μL, a CRP of 10 mg/dL, and no electrolyte imbalances, indicative of infection remission. His vital signs and respiratory function remained stable throughout his postoperative course, while the wound was inspected daily for signs of infection.

The patient was discharged on the second postoperative day. Follow-up was scheduled for one week postoperatively, to assess hernia repair and recovery, and he was instructed to continue oseltamivir twice daily until his appointment. The patient remained influenza-negative upon discharge, and all 12 exposed healthcare workers tested negative throughout 7-day surveillance.

The patient has not developed any postoperative or infection complications post-discharge and has shown no symptoms or signs of hernia recurrence to date.

DISCUSSION

Influenza A is the most prevalent strain to infect humans and the only one known to cause flu pandemics[12]. The virus primarily infects the upper and lower respiratory tract and can cause a range of complications including pneumonia, ARDS, cytokine storms, and exacerbation of preexisting lung conditions such as COPD[13]. Since 1968, most seasonal influenza epidemics have been caused by the H3N2 subtype[14], which typically causes more severe disease, particularly in elderly patients and those with underlying chronic comorbidities[15]. In our patient, the mild hypoxemia and dry cough were indicative of viral bronchitis, a complication commonly associated with H3N2 infection.

Surgery in patients with an active influenza infection is usually postponed for one to two weeks, although data on surgical outcomes in such patients is very limited for both children and adults[16-18]. The strongest evidence in literature is a 2023 propensity-score matched study including more than 30000 surgical patients, which concluded that a history of influenza infection in the first preoperative week increases the risk of postoperative pneumonia, septicaemia, acute renal failure, urinary tract infection, intensive care unit admission, and prolongs overall length of stay[19].

In our case, the urgency of hernia repair to avoid bowel ischaemia and sepsis overrode the risks associated with the influenza infection. In such emergency cases, general anaesthesia can be more complex depending on infection severity, due to potentially increased airway inflammation, decreased pulmonary reserve, and impaired oxygenation[20].

Moreover, a Swedish 2023 observational study over six influenza seasons revealed that the H3N2 subtype is associated with an increased risk of hospital dissemination[15]; additional infection prevention and control measures were therefore necessary in our case, although there are currently no established guidelines when operating on patients with influenza. In light of the COVID-19 pandemic, we decided to implement safety precautions recommended by guidelines for surgery of confirmed or suspected SARS-CoV-2 patients[21], considering the patient’s viral load was moderate. The absence of positive samples in consecutive healthcare staff testing in the first postoperative week in our report confirms the effectiveness and accuracy of implementation. Furthermore, multidisciplinary team discussion deemed robotic-assisted surgery safe considering the patient’s infection status, as cohort studies during the pandemic have validated its safety for COVID-19 patients[5].

Intraoperatively, the ventilation adaptations we applied to reduce the risk of viral aerosolisation and minimize exposure to the surgical team were additionally lung-protective and complemented by the reduction of pneumoperitoneum pressure. Pressures as low as 0.5 kPa (extremely-low-pressure or ULPP) have been successfully maintained during robotic-assisted general surgery and associated with reduced changes in intraoperative lung compliance, lower demand for postoperative analgesics, and improved quality of life during early stages of postoperative rehabilitation[22]. Studies utilising low-pressure pneumoperitoneum consider intraoperative emergencies (e.g. significant bleeding) as events necessitating intra-abdominal pressure elevation to 2.0-2.4 kPa for more than 2-5 minutes[23].

Beyond its technical feasibility, this case underscores the potential advantages of the robotic platform in managing high-risk patients with active respiratory infections. Robotic-assisted surgery offers enhanced precision, tremor filtration, and stable instrument control under low-pressure pneumoperitoneum, thereby minimizing the impact on pulmonary mechanics and reducing the risk of intraoperative hypoventilation[24]. In addition, the smaller incisions, improved ergonomics, and reduced postoperative pain contribute to earlier mobilization and better respiratory function in minimally invasive surgery overall[25]. Importantly, the physical separation of the console from the patient further limits aerosol exposure for the surgical team, an advantage highlighted during the COVID-19 pandemic. These factors collectively suggest that, when performed by an experienced team under strict infection control measures, the robotic platform may in fact enhance safety for both patient and staff in emergency surgery amidst active viral respiratory infections.

To our knowledge, our report describes the first robotic-assisted general surgery case to have been performed in a patient with an active respiratory tract infection in emergency settings. Nevertheless, it is still limited by the fact that it is a single case with short-term (< 1 year) follow-up. Although the Ct value for Influenza PCR was used to infer viral load, no detailed quantitative load assessment followed. Moreover, the case involved a patient with a specific set of comorbidities (such as elderly age, COPD, and diabetes) and a strangulated inguinal hernia, which may limit the generalisability of outcomes to other populations with different profiles. Lastly, we have implemented a series of protective measures for infection prevention and control, however no official guidelines have been established for robotic-assisted surgery amidst an active influenza infection.

Future research should therefore focus on tailoring robotic surgical protocols to better prepare operators for potential influenza pandemics, and investigate the role of robotic-assisted general surgery in larger patient cohorts with active infections and even consider the exploration of advanced technologies such as artificial intelligence and augmented reality[26]. Until then, we believe that the present case report is a strong first indication that the robotic platform is a feasible alternative to open surgery in patients with respiratory infections in emergency situations, and safe for both patients and healthcare professionals when strict infection prevention and control measures are enacted.

CONCLUSION

This case represents the first reported experience of emergency robotic-assisted repair of a strangulated hernia in an elderly patient with multiple comorbidities and active influenza A (H3N2) infection. It suggests that, in carefully selected cases, robotic-assisted surgery may be a feasible option for managing complex surgical emergencies under high-risk conditions. Favorable perioperative outcomes in this case were associated with targeted anaesthetic and surgical adaptations, including lung-protective ventilation and ULPP, as well as strict adherence to infection-control protocols. While limited by its single-case nature, this report supports further investigation of emergency robotic-assisted surgery in patients with active respiratory infections through larger studies to better define indications, safety profiles, and standardized protocols.

References
1.  Reddy K, Gharde P, Tayade H, Patil M, Reddy LS, Surya D. Advancements in Robotic Surgery: A Comprehensive Overview of Current Utilizations and Upcoming Frontiers. Cureus. 2023;15:e50415.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in RCA: 110]  [Reference Citation Analysis (0)]
2.  Ibrahim Y, Rahman MA, Pickering O, Cole K, Pucher PH. Current evidence and reported experiences for robot-assisted emergency general surgery: systematic review. J Robot Surg. 2025;19:534.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Cited by in Crossref: 1]  [Cited by in RCA: 3]  [Article Influence: 3.0]  [Reference Citation Analysis (0)]
3.  Milone M, Anoldo P, de'Angelis N, Coccolini F, Khan J, Kluger Y, Sartelli M, Ansaloni L, Morelli L, Zanini N, Vallicelli C, Vigutto G, Moore EE, Biffl W, Catena F; ROEM Collaborative Group. The role of RObotic surgery in EMergency setting (ROEM): protocol for a multicentre, observational, prospective international study on the use of robotic platform in emergency surgery. World J Emerg Surg. 2024;19:20.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 1]  [Cited by in RCA: 7]  [Article Influence: 3.5]  [Reference Citation Analysis (0)]
4.  de'Angelis N, Khan J, Marchegiani F, Bianchi G, Aisoni F, Alberti D, Ansaloni L, Biffl W, Chiara O, Ceccarelli G, Coccolini F, Cicuttin E, D'Hondt M, Di Saverio S, Diana M, De Simone B, Espin-Basany E, Fichtner-Feigl S, Kashuk J, Kouwenhoven E, Leppaniemi A, Beghdadi N, Memeo R, Milone M, Moore E, Peitzmann A, Pessaux P, Pikoulis M, Pisano M, Ris F, Sartelli M, Spinoglio G, Sugrue M, Tan E, Gavriilidis P, Weber D, Kluger Y, Catena F. Robotic surgery in emergency setting: 2021 WSES position paper. World J Emerg Surg. 2022;17:4.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 84]  [Cited by in RCA: 78]  [Article Influence: 19.5]  [Reference Citation Analysis (0)]
5.  Sparwasser P, Brandt MP, Haack M, Dotzauer R, Boehm K, Gheith MK, Mager R, Jäger W, Ziebart A, Höfner T, Tsaur I, Haferkamp A, Borgmann H. Robotic surgery can be safely performed for patients and healthcare workers during COVID-19 pandemic. Int J Med Robot. 2021;17:e2291.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 3]  [Cited by in RCA: 5]  [Article Influence: 1.0]  [Reference Citation Analysis (0)]
6.  Peng L, Liu J, Xu W, Luo Q, Chen D, Lei Z, Huang Z, Li X, Deng K, Lin B, Gao Z. SARS-CoV-2 can be detected in urine, blood, anal swabs, and oropharyngeal swabs specimens. J Med Virol. 2020;92:1676-1680.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 207]  [Cited by in RCA: 282]  [Article Influence: 47.0]  [Reference Citation Analysis (0)]
7.  Vigneswaran Y, Prachand VN, Posner MC, Matthews JB, Hussain M. What Is the Appropriate Use of Laparoscopy over Open Procedures in the Current COVID-19 Climate? J Gastrointest Surg. 2020;24:1686-1691.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 122]  [Cited by in RCA: 128]  [Article Influence: 21.3]  [Reference Citation Analysis (0)]
8.  Porter J, Blau E, Gharagozloo F, Martino M, Cerfolio R, Duvvuri U, Caceres A, Badani K, Bhayani S, Collins J, Coelho R, Rocco B, Wiklund P, Nathan S, Parra-Davila E, Ortiz-Ortiz C, Maes K, Dasgupta P, Patel V. Society of Robotic Surgery review: recommendations regarding the risk of COVID-19 transmission during minimally invasive surgery. BJU Int. 2020;126:225-234.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 32]  [Cited by in RCA: 36]  [Article Influence: 6.0]  [Reference Citation Analysis (0)]
9.  Person B, Bahouth H, Brauner E, Ben-Ishay O, Bickel A, Kluger YS. Surgical emergencies confounded by H1N1 influenza infection - a plea for concern. World J Emerg Surg. 2010;5:6.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 6]  [Cited by in RCA: 7]  [Article Influence: 0.4]  [Reference Citation Analysis (0)]
10.  Baheer Y, Isherwood L, Warner R, Teoh J, Decaestecker K, Dasgupta P, Tillinghast W, Trutza G, Vasdev N. Impact of low-pressure pneumoperitoneum on post-operative pain in robotic urological surgery: a systematic review. J Robot Surg. 2025;19:72.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Cited by in Crossref: 1]  [Cited by in RCA: 3]  [Article Influence: 3.0]  [Reference Citation Analysis (0)]
11.  Acute Respiratory Distress Syndrome Network, Brower RG, Matthay MA, Morris A, Schoenfeld D, Thompson BT, Wheeler A. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med. 2000;342:1301-1308.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Cited by in Crossref: 10292]  [Cited by in RCA: 8352]  [Article Influence: 321.2]  [Reference Citation Analysis (4)]
12.  Elderfield R, Barclay W. Influenza pandemics. Adv Exp Med Biol. 2011;719:81-103.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 13]  [Cited by in RCA: 20]  [Article Influence: 1.3]  [Reference Citation Analysis (0)]
13.  Mallia P, Johnston SL. Influenza infection and COPD. Int J Chron Obstruct Pulmon Dis. 2007;2:55-64.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 13]  [Cited by in RCA: 50]  [Article Influence: 2.8]  [Reference Citation Analysis (0)]
14.  Jester BJ, Uyeki TM, Jernigan DB. Fifty Years of Influenza A(H3N2) Following the Pandemic of 1968. Am J Public Health. 2020;110:669-676.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Cited by in Crossref: 78]  [Cited by in RCA: 98]  [Article Influence: 16.3]  [Reference Citation Analysis (0)]
15.  Rothman E, Olsson O, Christiansen CB, Rööst M, Inghammar M, Karlsson U. Influenza A subtype H3N2 is associated with an increased risk of hospital dissemination - an observational study over six influenza seasons. J Hosp Infect. 2023;139:134-140.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Cited by in RCA: 7]  [Reference Citation Analysis (0)]
16.  Malviya S, Voepel-Lewis T, Siewert M, Pandit UA, Riegger LQ, Tait AR. Risk factors for adverse postoperative outcomes in children presenting for cardiac surgery with upper respiratory tract infections. Anesthesiology. 2003;98:628-632.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Cited by in Crossref: 56]  [Cited by in RCA: 41]  [Article Influence: 1.8]  [Reference Citation Analysis (0)]
17.  von Ungern-Sternberg BS, Boda K, Chambers NA, Rebmann C, Johnson C, Sly PD, Habre W. Risk assessment for respiratory complications in paediatric anaesthesia: a prospective cohort study. Lancet. 2010;376:773-783.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Cited by in Crossref: 357]  [Cited by in RCA: 345]  [Article Influence: 21.6]  [Reference Citation Analysis (0)]
18.  Canet J, Gallart L, Gomar C, Paluzie G, Vallès J, Castillo J, Sabaté S, Mazo V, Briones Z, Sanchis J; ARISCAT Group. Prediction of postoperative pulmonary complications in a population-based surgical cohort. Anesthesiology. 2010;113:1338-1350.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Cited by in Crossref: 1124]  [Cited by in RCA: 898]  [Article Influence: 56.1]  [Reference Citation Analysis (0)]
19.  Lam F, Liao CC, Chen TL, Huang YM, Lee YJ, Chiou HY. Outcomes after surgery in patients with and without recent influenza: a nationwide population-based study. Front Med (Lausanne). 2023;10:1117885.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Cited by in RCA: 6]  [Reference Citation Analysis (0)]
20.  Bhattacharya S, Agarwal S, Shrimali NM, Guchhait P. Interplay between hypoxia and inflammation contributes to the progression and severity of respiratory viral diseases. Mol Aspects Med. 2021;81:101000.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 6]  [Cited by in RCA: 22]  [Article Influence: 4.4]  [Reference Citation Analysis (0)]
21.  Lee JS, Yum HK, Si HJ, Han SH, Park SY, Peck KR, Eom JS; Korean Society of Infectious Diseases (KSID);  Korea Medical Association Task Force Expert Committee. Guidelines for Surgery of Confirmed or Suspected COVID-19 Patients. Infect Chemother. 2020;52:453-459.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 2]  [Cited by in RCA: 4]  [Article Influence: 0.7]  [Reference Citation Analysis (0)]
22.  Park SE, Hong TH. Effects of extremely low-pressure pneumoperitoneum on postoperative recovery after single site robot-assisted cholecystectomy: a randomized controlled trial. Langenbecks Arch Surg. 2023;408:242.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Cited by in RCA: 3]  [Reference Citation Analysis (0)]
23.  Kostakopoulos N, Athanasiadis G, Omar MI, Abraham J, Dimitropoulos K. The impact of low-pressure pneumoperitoneum on robotic-assisted radical cystectomy and intracorporeal ileal conduit urinary diversion: a case-control study. World J Urol. 2022;40:2467-2472.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 2]  [Cited by in RCA: 4]  [Article Influence: 1.0]  [Reference Citation Analysis (0)]
24.  Petropoulou T, Evangelou K, Polydorou A. Expanding the boundaries of minimally invasive surgery: the feasibility of robotic natural orifice transluminal extraction colectomy and robotic no-incision colectomy in colorectal practice. Ann Coloproctol. 2025;41:346-353.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 1]  [Cited by in RCA: 4]  [Article Influence: 4.0]  [Reference Citation Analysis (0)]
25.  Petropoulou T, Fotiadou A, Evangelou K, Krasicka D, Polydorou A, Konstantoulakis M. Emergency Laparoscopy for Complex and Trauma Cases: Feasibility and Outcomes in Experienced Surgical Teams. Cureus. 2025;17:e91138.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in Crossref: 1]  [Cited by in RCA: 2]  [Article Influence: 2.0]  [Reference Citation Analysis (0)]
26.  Petropoulou T, Backer P, Evangelou K, Simoens J, Polydorou A, Mottrie A. Technical implementation and feasibility of the world's first artificial intelligence-assisted augmented reality-based instrument de-occlusion in robotic-assisted right hemicolectomy. Ann Coloproctol. 2025;41:483-488.  [RCA]  [PubMed]  [DOI]  [Full Text]  [Full Text (PDF)]  [Cited by in RCA: 2]  [Reference Citation Analysis (0)]
Footnotes

Peer review: Externally peer reviewed.

Peer-review model: Single blind

Specialty type: Virology

Country of origin: Greece

Peer-review report’s classification

Scientific quality: Grade B, Grade C

Novelty: Grade B, Grade C

Creativity or innovation: Grade B, Grade C

Scientific significance: Grade B, Grade C

P-Reviewer: Ye L, MD, PhD, Professor, China S-Editor: Liu H L-Editor: A P-Editor: Wang CH

Write to the Help Desk