Study characteristics on health-related quality of life in older people living with human immunodeficiency virus: A narrative review

doi:10.5501/wjv.v14.i3.111071

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World Journal of Virology

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2220-3249

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Virol. Sep 25, 2025; 14(3): 111071
Published online Sep 25, 2025. doi: 10.5501/wjv.v14.i3.111071

Study characteristics on health-related quality of life in older people living with human immunodeficiency virus: A narrative review

Phan Sok, Mary V Seeman, Sean B Rourke

Phan Sok, Temerty Faculty of Medicine, Institute of Medical-Science, University of Toronto, Toronto M5S 1A8, Ontario, Canada

Mary V Seeman, Sean B Rourke, Department of Psychiatry, University of Toronto, Toronto M5T 1R8, Ontario, Canada

Sean B Rourke, MAP, Center for Urban Health Solutions, St. Michael’s Hospital, Toronto M5B 1W8, Ontario, Canada

Author contributions: Sok P researched the content, conceived the idea, and designed the narrative review as part of his doctoral studies at the Institute of Medical Sciences, University of Toronto, Toronto, Canada. He conducted the literature search, evaluated the narrative review process and results, drafted the initial manuscript, and revised the manuscript. Seeman VS and Rourke SB provided critical input, reviewed, and edited the first draft and subsequent revisions of the manuscript.

Conflict-of-interest statement: All authors declare no potential conflicts of interest.

PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Phan Sok, MD, Academic Fellow, Doctorate Student, Temerty Faculty of Medicine, Institute of Medical-Science, University of Toronto, One King’s College Circle, Toronto M5S 1A8, Ontario, Canada. phan.sok@gmail.com

Received: June 23, 2025
Revised: August 2, 2025
Accepted: September 2, 2025
Published online: September 25, 2025
Processing time: 95 Days and 7.5 Hours

Core Tip

Core Tip: This narrative review aims to identify gaps in current studies on health-related quality of life in the context of human immunodeficiency virus and aging. It focuses on demographics, methodologies, and outcomes to provide a comprehensive understanding of existing research gaps for future studies in this area. The review reveals imbalances and limitations including study locations, demographics, sample sizes, utilization of conceptual frameworks, measuring instruments, and determinants associated with outcomes.