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World J Virol. Jun 25, 2025; 14(2): 102674
Published online Jun 25, 2025. doi: 10.5501/wjv.v14.i2.102674
COVID-19 management in patients with comorbid conditions
Adekunle Sanyaolu, Chuku Okorie, Aleksandra Marinkovic, Stephanie Prakash, Vyshnavy Balendra, Amine Lehachi, Abu Fahad Abbasi, Nafees Haider, Amos Abioye, Verner N Orish, Afolabi Antonio, Olanrewaju Badaru, Rajashree Pandit, Ricardo Izurieta
Adekunle Sanyaolu, Chuku Okorie, Rajashree Pandit, Department of Biomedical Science, D’Youville University, Buffalo, NY 14201, United States
Aleksandra Marinkovic, Stephanie Prakash, Vyshnavy Balendra, Amine Lehachi, Department of Basic Medical Science, Saint James School of Medicine, The Quarter 2640, Anguilla
Abu Fahad Abbasi, Department of Internal Medicine, Loyola University Medical Center, Maywood, IL 60153, United States
Nafees Haider, Department of Basic Science, All Saints University School of Medicine, Roseau 00152, Dominica
Amos Abioye, College of Pharmacy and Health Sciences, Belmont University, Nashville, TN 37212, United States
Verner N Orish, Department of Microbiology and Immunology, School of Medicine, University of Health and Allied Sciences, Ho PMB31, Ghana
Afolabi Antonio, Department of Medicine, Lloydminster Regional Hospital, Lloydminster S9V 1Y5, Saskatchewan, Canada
Olanrewaju Badaru, Department of Public Health, Federal Ministry of Health, Abuja 083, Federal Capital Territory, Nigeria
Ricardo Izurieta, School of Public Health and Health Sciences, California State University, Los Angeles, CA 90747, United States
Author contributions: Sanyaolu A contributed to conceptualization and design, approved the final version, and responsible for the accuracy and integrity of all the aspects of the research; Marinkovic A, Prakash S, Balendra V, Lehachi A, Abbasi AF, and Haider N contributed to drafting of the article; Marinkovic A contributed to project administration; Okorie C, Abioye A, Orish VN, Antonio A, Badaru O, Pandit R, and Izurieta R contributed to review and revise the article for intellectual content and editing.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Adekunle Sanyaolu, PhD, Professor, Department of Biomedical Science, D’Youville University, 320 Porter Avenue, Buffalo, NY 14201, United States. sanyakunle@hotmail.com
Received: October 27, 2024
Revised: March 16, 2025
Accepted: April 28, 2025
Published online: June 25, 2025
Processing time: 241 Days and 5.8 Hours
Core Tip

Core Tip: Effective management of coronavirus disease 2019 in patients with comorbid conditions is vital to reduce severe complications, limit hospitalizations and ease the pressure on healthcare systems. This requires employing thorough diagnostic methods, tailoring pharmacological treatments to individual patient profiles, and encouraging widespread vaccination to boost immunity efforts. An integrated approach ensures better patient outcomes and supports public health resilience during ongoing and future infectious disease challenges.