Disclosure and peer support in prevention of mother-to-child transmission of human immunodeficiency virus: Evidence from Rwanda

doi:10.5501/wjv.v14.i4.111700

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Dec 25, 2025 (publication date) through Feb 24, 2026

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World Journal of Virology

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2220-3249

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Virol. Dec 25, 2025; 14(4): 111700
Published online Dec 25, 2025. doi: 10.5501/wjv.v14.i4.111700

Disclosure and peer support in prevention of mother-to-child transmission of human immunodeficiency virus: Evidence from Rwanda

Saurav Basu

Saurav Basu, Community Medicine, ESI-PGIMSR Medical College and Hospital - Joka, Kolkata 700104, West Bengal, India

Author contributions: All contributions by single author.

Conflict-of-interest statement: The author declares no conflict of interest.

Corresponding author: Saurav Basu, MD, Assistant Professor, Community Medicine, ESI-PGIMSR Medical College and Hospital - Joka, Diamond Harbor Road, Kolkata 700104, West Bengal, India. saurav.basu1983@gmail.com

Received: July 7, 2025
Revised: August 11, 2025
Accepted: September 24, 2025
Published online: December 25, 2025
Processing time: 171 Days and 13.3 Hours

Abstract

This retrospective cohort study from Rwanda demonstrated the likelihood of maternal disclosure and peer support in preventing mother-to-child human immunodeficiency virus (HIV) transmission. High sustained maternal viral load suppression (91.0%) and exceptional infant testing uptake (100% at 6 weeks) correlated with a low 0.7% infant HIV incidence. To eliminate mother-to-child transmission of HIV, effective strategies must engage male partners in disclosure, reduce stigma, improve health literacy, and provide structural peer-support for enhancing adherence and mental health.

Keywords: Prevention of mother-to-child transmission; Disclosure (human immunodeficiency virus status); Peer support; Human immunodeficiency virus/Acquired immunodeficiency syndrome; Adherence

Core Tip: Maternal disclosure and peer support are effective in preventing mother-to-child human immunodeficiency virus transmission.