Outcomes and complications of combined heart-liver transplantation in patients with failing Fontan physiology: A systematic review

doi:10.5500/wjt.v15.i4.106444

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Dec 18, 2025 (publication date) through Nov 19, 2025

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Transplant. Dec 18, 2025; 15(4): 106444
Published online Dec 18, 2025. doi: 10.5500/wjt.v15.i4.106444

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Figure 1 PRISMA flow diagram detailing the study identification, screening, eligibility, and inclusion process for the systematic review and meta-analysis.

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Figure 2 Forest plots for cumulative intensive care unit length of stay, hospital length of stay, cardiopulmonary bypass time, and ischemic time for combined heart-liver transplantation-only patients.

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Figure 3 Forest plot comparing intensive care unit length of stay, hospital length of stay, cardiopulmonary bypass time, ischemic time, and overall mortality. CHLT: Combined heart-liver transplantation.

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Figure 4 Forest plot comparing post-transplant complications, including infection rates, acute kidney injury, and cardiac rejection between combined heart-liver transplantation and orthotopic heart transplantation patients. CHLT: Combined heart-liver transplantation.

Citation: Shahzil M, Habiba U, Irfan MZ, Qureshi MA, Faisal MS, Kashif T, Qureshi AA, Ali H, Jahagirdar V, Vinayek R. Outcomes and complications of combined heart-liver transplantation in patients with failing Fontan physiology: A systematic review. World J Transplant 2025; 15(4): 106444
URL: https://www.wjgnet.com/2220-3230/full/v15/i4/106444.htm
DOI: https://dx.doi.org/10.5500/wjt.v15.i4.106444