Ardila CM, González-Arroyave D, Ramírez-Arbelaez J. Robotic-assisted donor and recipient hepatectomy in liver transplantation: An umbrella review of clinical outcomes, surgical performance, and cost-effectiveness. World J Transplant 2026; 16(1): 113034 [DOI: 10.5500/wjt.v16.i1.113034]
Corresponding Author of This Article
Carlos M Ardila, DDS, PhD, Department of Basic Sciences, Biomedical Stomatology Research Group, Faculty of Dentistry, Universidad de Antioquia, Calle 70 No. 52-21, Medellin 050010, Antioquia, Colombia. martin.ardila@udea.edu.co
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Medicine, Research & Experimental
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Systematic Reviews
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Mar 18, 2026 (publication date) through Jan 14, 2026
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Publication Name
World Journal of Transplantation
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2220-3230
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Ardila CM, González-Arroyave D, Ramírez-Arbelaez J. Robotic-assisted donor and recipient hepatectomy in liver transplantation: An umbrella review of clinical outcomes, surgical performance, and cost-effectiveness. World J Transplant 2026; 16(1): 113034 [DOI: 10.5500/wjt.v16.i1.113034]
World J Transplant. Mar 18, 2026; 16(1): 113034 Published online Mar 18, 2026. doi: 10.5500/wjt.v16.i1.113034
Robotic-assisted donor and recipient hepatectomy in liver transplantation: An umbrella review of clinical outcomes, surgical performance, and cost-effectiveness
Carlos M Ardila, Daniel González-Arroyave, Jaime Ramírez-Arbelaez
Carlos M Ardila, Department of Basic Sciences, Biomedical Stomatology Research Group, Faculty of Dentistry, Universidad de Antioquia, Medellin 050010, Antioquia, Colombia.
Carlos M Ardila, Department of Periodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 600077, Tamil Nadu, India
Daniel González-Arroyave, Department of Surgery, Universidad Pontificia Bolivariana, Medellín 050031, Antioquia, Colombia
Jaime Ramírez-Arbelaez, Department of Transplantation, Hospital San Vicente Fundación, Rionegro 0057, Antioquia, Colombia
Author contributions: Ardila CM performed the conceptualization and manuscript writing; Ardila CM, González-Arroyave D, and Ramírez-Arbeláez J performed the data curation, data analysis, and revision of the manuscript.
Conflict-of-interest statement: All authors declare having no conflicts of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Carlos M Ardila, DDS, PhD, Department of Basic Sciences, Biomedical Stomatology Research Group, Faculty of Dentistry, Universidad de Antioquia, Calle 70 No. 52-21, Medellin 050010, Antioquia, Colombia. martin.ardila@udea.edu.co
Received: August 13, 2025 Revised: September 18, 2025 Accepted: November 26, 2025 Published online: March 18, 2026 Processing time: 154 Days and 10.9 Hours
Core Tip
Core Tip: This umbrella review separates donor (direct) from recipient/economic (indirect) evidence and standardizes effect reporting, heterogeneity, and grading of recommendations assessment, development and evaluation (GRADE). Donor robotics reduces blood loss and length of stay but lengthens operative time. Recipient robotics shows fewer conversions to open intervention and lower severe morbidity, with no mortality difference. Economic contrasts are context-dependent, with higher procedural but lower hospitalization costs for robotic vs open, and laparoscopy the least expensive overall. The Preferred Reporting Items for Systematic reviews and Meta-Analyses counts, citation-matrix/corrected covered area, AMSTAR 2, and outcome-level GRADE profiles are provided to ensure an audit-ready package and to map evidence gaps that future transplant-specific studies must address.
