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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Dec 18, 2025; 15(4): 106812
Published online Dec 18, 2025. doi: 10.5500/wjt.v15.i4.106812
Published online Dec 18, 2025. doi: 10.5500/wjt.v15.i4.106812
Endocrine-related neurological function recovery in pancreatic transplantation
Shuai-Yan Wang, Zi-Mu Li, Meng-Zhe Zhang, Zi-Ming Chen, Xin Liu, Ya-Jing Li, Pei-Yu Li, You-Bing Xia, Tian-Cheng Xu, Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province, China
Guan-Hu Yang, Department of Specialty Medicine, Ohio University, Athens, OH 45701, United States
Co-first authors: Shuai-Yan Wang and Zi-Mu Li.
Co-corresponding authors: Tian-Cheng Xu and You-Bing Xia.
Author contributions: Wang SY was responsible for the idea and conceptual framework; Wang SY, Li ZM, Zhang MZ, Chen ZM, Liu X, Li YJ, Li PY, and Yang GH wrote the first draft of the manuscript; Xia YB and Xu TC reviewed the manuscript and critically revised it for important intellectual content; all authors have reviewed and approved the final version of the manuscript.
Supported by National Natural Science Foundation of China, No. 82305376; and The Project of Supporting Young Scientific and Technological Talents in Jiangsu Province in 2024, No. JSTJ-2024-380.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest associated with the publication of this manuscript.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tian-Cheng Xu, MD, PhD, Associate Professor, Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, No. 138 Xianlin Avenue, Qixia District, Nanjing 210023, Jiangsu Province, China. xtc@njucm.edu.cn
Received: March 9, 2025
Revised: March 28, 2025
Accepted: April 24, 2025
Published online: December 18, 2025
Processing time: 255 Days and 17.4 Hours
Revised: March 28, 2025
Accepted: April 24, 2025
Published online: December 18, 2025
Processing time: 255 Days and 17.4 Hours
Core Tip
Core Tip: Pancreas transplantation (PT) helps improve glycemic control in diabetic patients and is crucial for neurological recovery and endocrine regulation. Research shows that nerve regeneration, immunosuppressive therapy side effects, and long-term health management of transplant recipients are key factors influencing transplant outcomes. Analyzing literature and patents provides insights for clinical practice, and future research should focus on relevant mechanisms to improve long-term PT success.