Copyright: ©Author(s) 2026.
World J Psychiatry. May 19, 2026; 16(5): 116452
Published online May 19, 2026. doi: 10.5498/wjp.v16.i5.116452
Published online May 19, 2026. doi: 10.5498/wjp.v16.i5.116452
Table 1 Commonly used antipsychotic medications
| Typical antipsychotics (first-generation) | Atypical antipsychotics (second-generation) |
| Phenothiazines: Chlorpromazine, fluphenazine, mesoridazine, perphenazine, thioridazine, trifluoperazine | Atypical agents: Aripiprazole, clozapine, olanzapine, quetiapine, risperidone, ziprasidone |
| Butyrophenones: Haloperidol | |
| Others: Loxapine, molindone, thiothixene |
Table 2 Prognostic indicators in schizophrenia
| Favorable prognostic indicators | Unfavorable prognostic indicators |
| Female sex | Male sex |
| Being married | Being single, divorced, or living alone |
| Acute onset | Insidious onset |
| Later age of onset | Early age of onset |
| Family history of mood disorder | Family history of schizophrenia |
| Good premorbid social adjustment | Premorbid schizoid or schizotypal personality |
| Living in a rural area | Living in an urban environment |
| Higher intelligence level | Lower intelligence level |
| Few and brief exacerbations | Frequent or prolonged hospitalizations |
| Early initiation and regular adherence to treatment | Irregular or absent treatment adherence |
| Absence of comorbid psychiatric disorders | Presence of comorbid psychiatric conditions |
| Strong family collaboration with the treatment team | Dysfunctional family environment or high expressed emotion |
- Citation: Ozsoy F, Tasci G, Tasci B, Dogan S, Tuncer T. Schizophrenia in the age of artificial intelligence: A review of advances in diagnosis, prediction, and digital psychiatry. World J Psychiatry 2026; 16(5): 116452
- URL: https://www.wjgnet.com/2220-3206/full/v16/i5/116452.htm
- DOI: https://dx.doi.org/10.5498/wjp.v16.i5.116452