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Randomized Controlled Trial
Copyright: ©Author(s) 2026.
World J Psychiatry. May 19, 2026; 16(5): 116043
Published online May 19, 2026. doi: 10.5498/wjp.v16.i5.116043
Table 1 Subject characteristics in participants with depression, n (%)
Variables
All (n = 100)
Age, years12 (10.25,14)
Sex
Men48 (48.0)
Women52 (52.0)
Obesity26 (26.0)
Sleep duration, minute, mean ± SD365.2 ± 64.4
Time in bed, minute, mean ± SD441.0 ± 56.5
Table 2 Subject characteristics in participants with depression, n (%)
Variables
Study group (n = 50)
Control group (n = 50)
P value
Age, years12.6 ± 2.311 (4)0.171
12.5 (11, 14)
Sex0.689
Men23 (46.0)25 (50.0)
Women27 (54.0)25 (50.0)
Obesity15 (30.0)11 (22.0)0.197
Sleep duration, minute, mean ± SD363.8 ± 68.5366.5 ± 60.70.524
Time in bed, minute, mean ± SD442.6 ± 56.3439.3 ± 56.70.421
Table 3 Comparison of side effects after treatment in two groups of patients, n (%)
Variables
Study group (n = 50)
Control group (n = 50)
P value
Extrapyramidal side effects0.743
Muscle stiffness3 (6)3 (6)
Tremor1 (2)2 (4)
Twisting movement1 (2)1 (2)
Immobility2 (4)1 (2)
Cholinergic side effects0.239
Dry mouth3 (6)4 (8)
Blurred vision5 (10)5 (10)
Stuffy nose4 (8)3 (6)
Salivation3 (6)4 (8)
Constipation4 (8)3 (6)


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