Clinical study of repetitive transcranial magnetic stimulation in the rehabilitation of post-stroke depression: A Quantitative Insomnia Sleep Inventory monitoring evaluation

Table 1 Comparison of the general characteristics of the two groups of patients at the time of enrollment, mean ± SD

Group	n	Gender		Length of education (years)	Marital status		Average duration of illness	Average age	Average weight
		Male	Female		Married	Unmarried
Control group	54	28	26	10.8 ± 3.2	51	3	2.7 ± 1.6	71.9 ± 6.6	61.9 ± 7.9
Observation group	54	27	27	9.9 ± 3.5	50	4	3.1 ± 1.9	72.4 ± 7.1	58.9 ± 8.0

Table 2 Comparison of Hamilton Depression Rating Scale-17 scores between the two groups before and after treatment, mean ± SD

Group	n	Before treatment	6 weeks after treatment	14 weeks after treatment
Control group	54	27.0 ± 6.0	17.9 ± 3.6a,b	13.9 ± 2.4c,d
Observation group	54	25.0 ± 5.0	24.0 ± 3.3	18.4 ± 3.5c

^aP < 0.05 vs control group at 6 weeks after treatment.

^bP < 0.01 vs control group at 6 weeks after treatment.

^cP < 0.05 vs control group at 14 weeks after treatment.

^dP < 0.01 vs control group at 14 weeks after treatment.

Table 3 Comparison of clinical efficacy between the two groups after treatment, n (%)

Group	n	Recovery (%)	Significant effect (%)	Effective (%)	Ineffective (%)	Total effective rate (%)
Control group	49	17 (34.7)	16 (32.7)	10 (20.4)	6 (14.2)	87.8a
Observation group	47	6 (14.8)	14 (25.5)	14 (29.8)	15 (31.9)	68.1

^aP < 0.05 vs control group.

Table 4 Comparison of Quantitative Insomnia Sleep Inventory between the two groups before and after treatment and healthy volunteers, mean ± SD

Group	n	Total sleep time (minutes)	Sleep latency (minutes)	Awakening time (minutes)	Wake to sleep ratio (%)	Sleep maintenance rate (%)	Sleep efficiency (%)
Observation group
Before treatment	54	425.9 ± 29.9	33.0 ± 17.4	37.7 ± 14.9	9.4 ± 4.0	90.0 ± 3.9	85.0 ± 9.0
14 weeks after treatment	49	417.9 ± 15.1a	17.9 ± 8.9b	18.9 ± 5.4b	5.7 ± 1.7	93.9 ± 1.9	97.4 ± 3.6b
Control group
Before treatment	54	426.0 ± 30.1	29.9 ± 14.9	35.7 ± 13.9	9.4 ± 3.9	87.9 ± 3.9	84.9 ± 8.9
14 weeks after treatment	47	372.4 ± 25.9c	32.7 ± 17.7c	42.9 ± 10.4c	6.0 ± 3.31	88.6 ± 4.1c	88.8 ± 8.9b
Healthy volunteer group	68	461.2 ± 16.9	20.1 ± 8.4	17.4 ± 5.5	4.8 ± 2.1	96.2 ± 3.7	94.1 ± 3.7
F		4.030	5.811	4.661	6.291	4.998	5.699
P value		0.010	0.003	0.007	0.003	0.004	0.002

^aP < 0.05 vs before treatment.

^bP < 0.05 vs the control group 14 weeks after treatment.

^cP < 0.05 vs the healthy volunteer group.

¹Five patients dropped out in the observation group after three months follow-up.