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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
World J Psychiatry. Mar 19, 2026; 16(3): 116094
Published online Mar 19, 2026. doi: 10.5498/wjp.v16.i3.116094
Clinical study of repetitive transcranial magnetic stimulation in the rehabilitation of post-stroke depression: A Quantitative Insomnia Sleep Inventory monitoring evaluation
Ai-Ming Gu, Chao Liu, Jian-Hong Chen, Ru-Ya Guo, Chao Liang, Xing-Shi Chen
Ai-Ming Gu, Department of Neurology, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing 314000, Zhejiang Province, China
Chao Liu, Department of Psychiatry, The First Hospital of Jiaxing, Jiaxing 314000, Zhejiang Province, China
Jian-Hong Chen, Department of Medical, Jinhua City Durg Rehabilitation Isolation Center, Jinhua 321000, Zhejiang Province, China
Ru-Ya Guo, Department of Endocrinology, The First Hospital of Jiaxing, Jiaxing 314000, Zhejiang Province, China
Chao Liang, Department of General Practice, The First Hospital of Jiaxing, Jiaxing 314000, Zhejiang Province, China
Xing-Shi Chen, Department of Electrophysiology, Shanghai Mental Health Center, Shanghai 200030, China
Co-first authors: Ai-Ming Gu and Chao Liu.
Co-corresponding authors: Jian-Hong Chen and Ru-Ya Guo.
Author contributions: Gu AM and Chen JH designed the study; Gu AM, Guo RY, and Chen XS conducted the research; Chen JH and Chen XS provided experimental instruments; Liu C, Chen JH, and Liang C analyzed the data and drafted the manuscript; Gu AM and Liu C contributed equally to this manuscript and are co-first authors; Chen JH and Guo RY contributed equally to this manuscript and are co-corresponding authors. All authors have read and approved the final manuscript.
Supported by National Natural Science Foundation of China, No. 81471357; and the Project of Jinhua Municipal Bureau of Science and Technology, No. 2024-07 and No. 2024-08.
Institutional review board statement: This study was reviewed and approved by the Medical Ethics Committee of Shanghai Mental Health Center (Approval No. 2019009).
Informed consent statement: All participants in the study signed the informed consent form before commencement of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: No additional data are available.
Corresponding author: Jian-Hong Chen, Department of Medical, Jinhua City Durg Rehabilitation Isolation Center, No. 1 Fangjingtou Community, Fangjingtou Village, Wucheng District, Jinhua 321000, Zhejiang Province, China. 18713190@qq.com
Received: November 7, 2025
Revised: December 8, 2025
Accepted: February 5, 2026
Published online: March 19, 2026
Processing time: 111 Days and 23.1 Hours
Core Tip

Core Tip: This study examined the role of combined application of repetitive transcranial magnetic stimulation (rTMS) and Quantitative Insomnia Sleep Inventory (QUISI) in the rehabilitation of post-stroke depression (PSD). Innovations included designing experiments based on China’s rTMS standards, using QUISI to evaluate therapeutic effects, developing monitoring protocols and quality plans, and adjusting technical parameters. The results showed that rTMS significantly increased the recovery and effective rates of PSD patients (evidenced by reduced Hamilton Depression Rating Scale-17 scores, and improved QUISI sleep efficiency and maintenance rate in the observation group). Thus, rTMS is effective for PSD, and QUISI can be used for rehabilitation assessment.