Clinical efficacy of Xifeng Huashi and its effect on mental status in patients with diarrheal irritable bowel

Table 1 Comparison of the general data of the two groups of patients

Characteristic	Research group (n = 64)	Control group (n = 64)	P value
Age (years)	43.45 ± 12.58	41.97 ± 11.71	0.400
Sex			0.246
Men	48 (75.00)	42 (65.63)
Female	16 (25.00)	22 (34.37)
BMI, kg/m2	23.16 ± 2.33	22.86 ± 2.62	0.573
Educational level			0.648
Primary school	28 (43.75)	21 (32.81)
Junior high school	16 (25.00)	19 (29.69)
Secondary and high school	12 (18.75)	15 (23.44)
College, bachelor's degree and above	8 (12.50)	9 (14.06)
Duration of disease (years)	4.56 ± 2.48	4.12 ± 2.19	0.195
History of using herbal medicine	14 (21.88)	18 (28.13)	0.414
Smoking history	22 (34.38)	19 (29.69)	0.570
Drinking history	26 (40.63)	24 (37.50)	0.717
Mean VAS score (cm)
Global IBS-D symptoms	6.86 ± 1.48	7.16 ± 1.36	0.146
Abdominal pain	5.52 ± 1.53	5.34 ± 1.47	0.407
Bloating	5.24 ± 1.32	5.06 ± 1.38	0.358
Urgency	5.88 ± 1.28	6.06 ± 1.40	0.354
Tiredness	4.14 ± 1.45	4.38 ± 1.52	0.265
Mean weekly stool frequency	16.26 ± 3.43	15.52 ± 3.51	0.142
Mean weekly Bristol score	6.03 ± 0.82	6.09 ± 0.77	0.657

Data were showed as n (%) or mean ± SD. BMI: Body mass index; VAS: Visual analog scale; IBS-D: Diarrheal irritable bowel syndrome.

Table 2 Comparison of overall efficacy between two groups of patients, n (%)

Classification	Recover	Remarkable effect	Efficiently	Not valid	Total effective number
Research group (n = 64)	21 (32.81)	20 (31.25)	18 (28.13)	5 (7.81)	59 (92.19)
Control group (n = 64)	14 (21.87)	16 (25.00)	19 (29.69)	15 (23.44)	49 (76.56)
χ2					5.926
P value					0.015

Table 3 The two patient groups were compared regarding their traditional Chinese medicine syndrome points (mean ± SD)

Classification treatment		Research group (n = 64)	Control group (n = 64)	t value	P value
Abdominal pain decreases after diarrhea	Before	3.12 ± 1.36	3.04 ± 1.21	0.431	0.668
	After	1.06 ± 0.78	1.61 ± 0.67	5.241	< 0.001
Irritable	Before	3.38 ± 1.64	3.44 ± 1.53	0.262	0.794
	After	1.36 ± 1.19	1.87 ± 1.02	3.188	0.002
Distension and fullness of both hypochondria regions	Before	2.32 ± 1.03	2.51 ± 1.12	1.223	0.223
	After	0.81 ± 0.72	1.27 ± 0.87	3.991	< 0.001
Anorexia	Before	2.63 ± 0.94	2.52 ± 1.08	0.753	0.453
	After	0.97 ± 0.39	1.32 ± 0.37	6.38	< 0.001
Tiredness and fatigue	Before	2.17 ± 0.88	2.24 ± 0.95	0.53	0.597
	After	0.89 ± 0.67	1.18 ± 0.73	2.868	0.005
Total points	Before	13.52 ± 3.39	13.75 ± 3.46	0.465	0.643
	After	5.07 ± 3.11	7.38 ± 3.68	4.698	< 0.001

Table 4 Recurrence rates compared between the two patient groups, n (%)

Classification	Effective number	Number of non-relapses	Number of relapses
Research group (n = 64)	59 (92.19)	48 (81.36)	11 (18.64)
Control group (n = 64)	49 (76.56)	29 (59.18)	20 (40.82)
χ2			6.430
P value			0.011