Efficacy and mechanism of Shugan Jieyu combined with sertraline in alcohol-dependent patients with depression: A randomized clinical study

Table 1 Intra-group comparisons of pre- and post-treatment depression scores (mean ± SD)

Group	n	Before treatment	At week 2	At week 4	At week 6
Control group	30	25.55 ± 4.93	23.00 ± 3.97	18.15 ± 4.19a	15.25 ± 4.67a
Study group	30	25.95 ± 4.26	19.65 ± 4.28a,b	14.10 ± 4.89a,b	11.35 ± 4.33a,b

^aP < 0.05 vs the scores before treatment.

^bP < 0.05 vs the scores of the control group.

Table 2 Comparison of efficacy rates of the two groups after treatment

Group	Number of effective cases	Number of ineffective cases	Total	χ2	P value
Control group	20	10	30
Study group	27	3	30	4.812	0.028
Total	47	13	60

Table 3 Comparison of Treatment Emergent Symptom Scale scores (mean ± SD) of the two groups

Period	Control group (n = 30)	Study group (n = 30)	F	P value
Week 2	6.25 ± 1.25	6.45 ± 1.43	0.423	0.767
Week 4	6.30 ± 1.45	6.25 ± 1.48	0.271	0.763
Week 6	5.05 ± 1.27	4.95 ± 1.43	0.058	0.943