Correlation between musculoskeletal system function and pre-depressive states in elderly cancer patients: A single-center cross-sectional study

Table 1 Comparison of the incidence of locomotive syndrome and subthreshold depression in elderly cancer patients with different characteristics

Variables	Classification	Total	LS			StD
			Number	χ2	P value	Number	χ2	P value
Gender	Male	218	102	5.546	0.062	86	6.455	0.053
	Female	265	171			101
Age	60-69	308	136	7.675	0.009	71	3.233	0.234
	70-79	128	95			75
	80-90	47	42			41
Residence	Live alone	75	13	2.011	0.321	11	1.232	0.348
	With co-residents	408	260			176
Comorbid chronic diseases	0	99	16	19.874	0.027	15	12.324	0.033
	1	188	86			58
	2	132	110			66
	≥ 3	64	61			48
BMI	Underweight	43	33	9.568	0.054	18	11.932	0.051
	Normal	304	145			122
	Overweight	106	72			33
	Obesity	30	23			14
Regular exercise habits	None	324	215	5.478	0.021	163	2.534	0.038
	Yes	159	58			24
Type of former occupation	Physical work	163	68	4.684	0.042	72	5.457	0.076
	Non-physical work	320	205			115
Cancer metastasis	None	306	104	7.857	0.002	87	6.232	0.031
	Yes	177	169			100
Operation history	None	279	123	9.876	0.061	76	7.624	0.122
	Yes	204	150			111
Radiotherapy history	None	302	172	7.643	0.058	89	9.384	0.122
	Yes	181	180			98
Chemotherapy history	None	67	12	8.582	0.072	7	7.893	0.122
	Yes	416	261			180
StD	None	296	121	23.324	< 0.001
	Yes	187	152
LS	None	210				35	21.132	< 0.001
	Yes	273				152

BMI: Body mass index; LS: Locomotive syndrome; StD: Subthreshold depression.

Table 2 Independent variable assignment

Independent variable	Assignment method
Age	60-69 = 0; 70-79 = 1; 80-90 = 2
Regular exercise habits	None = 0; yes = 1
Type of former occupation	Non-physical work = 0; physical work = 1
Cancer metastasis	None = 0; yes = 1
Comorbid chronic diseases	0 = 0; 1 = 1; 2 = 2; ≥ 3 = 3
StD	None = 0; yes = 1

StD: Subthreshold depression.

Table 3 Logistic regression analysis of locomotive syndrome in elderly cancer patients

Variables	β	SE	χ2	P value	OR	95%CI
Constant	-3.245	0.477	48.347	< 0.001	N/A	N/A
Age (60-69 as reference)
70-79	0.559	0.281	3.969	0.046	1.749	1.009-3.032
80-90	1.311	0.610	4.614	0.022	3.709	1.122-12.266
Cancer metastasis (none as reference)
Yes	0.403	0.384	1.102	0.026	0.668	0.314-1.421
Regular exercise habits (none as reference)
Yes	-0.403	0.384	1.102	0.038	0.668	0.314-1.421
StD (none as reference)
Yes	1.209	0.272	19.728	< 0.001	3.228	1.966-5.714

StD: Subthreshold depression; OR: Odd ratio; CI: Confidence internal; N/A: Not applicable.

Table 4 Independent variable assignment

Independent variable	Assignment method
Regular exercise habits	None = 0; yes = 1
Cancer metastasis	None = 0; yes = 1
Comorbid chronic diseases	0 = 0; 1 = 1; 2 = 2; ≥ 3 = 3
LS	None = 0; yes = 1

LS: Locomotive syndrome.

Table 5 Logistic regression analysis of factors influencing subthreshold depression in elderly cancer patients

Variables	β	SE	χ2	P value	OR	95%CI
Constant	-2.187	0.545	39.113	< 0.001	N/A	N/A
Comorbid chronic diseases (0 as reference)
1	0.628	0.424	2.193	0.139	1.874	0.816-4.301
2	0.486	0.448	1.179	0.278	1.626	0.676-3.913
≥ 3	1.291	0.395	10.688	0.001	3.521	1.677-7.886
LS (none as reference)
Yes	1.187	0.279	18.123	< 0.001	3.102	1.898-5.662

LS: Locomotive syndrome; OR: Odd ratio; N/A: Not applicable; CI: Confidence internal.

Table 6 Correlation of subthreshold depression and dimensions with 25-question Geriatric Locomotive Function Scale

Variables	R	P value
GLFS-25	0.424	< 0.001
Pain	0.302	< 0.001
Daily living activities	0.319	< 0.001
Social function	0.435	< 0.001
Mental health	0.439	< 0.001

GLFS-25: 25-question Geriatric Locomotive Function Scale.