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World J Psychiatry. Aug 19, 2026; 16(8): 119137
Published online Aug 19, 2026. doi: 10.5498/wjp.119137
Published online Aug 19, 2026. doi: 10.5498/wjp.119137
Impact of comorbid depression on treatment adherence and long-term urinary function following surgery for benign prostatic hyperplasia
Wen-Chao Dun, Qiang Xia, Cheng-Bai Li, Department of Urology, Wuxi Ninth People’s Hospital Affiliated to Soochow University, Wuxi 214000, Jiangsu Province, China
Zhong-Qing Wei, Department of Urology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210000, Jiangsu Province, China
Author contributions: Dun WC performed research and wrote the manuscript; Xia Q and Wei ZQ analyzed data; Li CB conceived the research, and provided guidance for the research. All authors reviewed and approved the final manuscript.
Supported by Wuxi Municipal Health Commission General Project, No. M202459.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of Wuxi Ninth People’s Hospital Affiliated to Soochow University (approval No. KS2024067).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Corresponding author: Cheng-Bai Li, Associate Chief Physician, Researcher, Department of Urology, Wuxi Ninth People’s Hospital Affiliated to Soochow University, No. 999 Liangxi Road, Binhu District, Wuxi 214000, Jiangsu Province, China. 15961770137@163.com
Received: March 6, 2026
Revised: March 30, 2026
Accepted: May 27, 2026
Published online: August 19, 2026
Processing time: 134 Days and 9.2 Hours
Revised: March 30, 2026
Accepted: May 27, 2026
Published online: August 19, 2026
Processing time: 134 Days and 9.2 Hours
Core Tip
Core Tip: This retrospective study found that comorbid depression is an independent predictor of poor treatment adherence among patients undergoing surgery for benign prostatic hyperplasia. Reduced adherence was associated with impaired long-term recovery of urinary function after surgery. These findings highlight the importance of routine psychological assessment and early identification of depressive symptoms in this patient population. Implementing targeted psychological and behavioral interventions may improve treatment compliance, enhance postoperative recovery outcomes, and support long-term urinary function rehabilitation in patients with benign prostatic hyperplasia.