Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Psychiatry. Aug 19, 2026; 16(8): 116766
Published online Aug 19, 2026. doi: 10.5498/wjp.116766
Published online Aug 19, 2026. doi: 10.5498/wjp.116766
Analysis of the preventive effect of evidence-based, non-pharmacological care bundles against delirium in intensive care unit patients
Yu-Ting Xiao, Xiao-Yue Wang, Juan Huang, Intensive Care Unit, Chongqing General Hospital, Chongqing 401147, China
Co-first authors: Yu-Ting Xiao and Xiao-Yue Wang.
Author contributions: Xiao YT and Wang XY designed the research, wrote the first manuscript, conducted the analysis and provided guidance for the research as co-first authors; Xiao YT, Wang XY, and Huang J contributed to conceiving the research and analyzing data; all authors reviewed and approved the final manuscript.
Supported by Chongqing Municipal Science and Technology Health Joint Medical Research Project (General Program), No. 2023MSXM052.
Institutional review board statement: The study has obtained approval from the Ethics Committee of Chongqing General Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Data sharing statement: No additional data are available.
Corresponding author: Juan Huang, MD, Professor, Intensive Care Unit, Chongqing General Hospital, No. 118 Xingguang Avenue, Liangjiang New Area, Chongqing 401147, China.
Received: January 13, 2026
Revised: March 10, 2026
Accepted: April 27, 2026
Published online: August 19, 2026
Processing time: 190 Days and 7.2 Hours
Revised: March 10, 2026
Accepted: April 27, 2026
Published online: August 19, 2026
Processing time: 190 Days and 7.2 Hours
Core Tip
Core Tip: This study aimed to optimize and strengthen delirium management in intensive care unit-hospitalized patients by implementing evidence-based, non-pharmacological care bundles. Through comprehensive analyses, this model was found to be effective in preventing delirium, reducing nursing-related complications, and accelerating recovery. It also significantly improved cognitive function, sleep quality, and overall health status. The intervention is both safe and effective, with profound clinical implications.