Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Psychiatry. May 19, 2026; 16(5): 115152
Published online May 19, 2026. doi: 10.5498/wjp.v16.i5.115152
Published online May 19, 2026. doi: 10.5498/wjp.v16.i5.115152
Post-stroke seizures and epilepsy: Risk factors, neuropsychiatric outcomes, and a management framework
Emre Kudu, Mustafa Altun, Department of Emergency Medicine, Marmara University School of Medicine, İstanbul 34899, Pendik, Türkiye
Author contributions: Kudu E designed the overall concept, outline, and manuscript design; led the writing; Altun M contributed to the discussion, edited the manuscript; Kudu E and Altun M contributed to the review of the literature. All authors approved the final version to be published.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Emre Kudu, MD, Assistant Professor, Department of Emergency Medicine, Marmara University Pendik Training and Research Hospital, Fevzi Çakmak, Muhsin Yazıcıoğlu Cd 10, İstanbul 34899, Pendik, Türkiye. dr.emre.kudu@gmail.com
Received: October 9, 2025
Revised: November 3, 2025
Accepted: December 19, 2025
Published online: May 19, 2026
Processing time: 202 Days and 12.7 Hours
Revised: November 3, 2025
Accepted: December 19, 2025
Published online: May 19, 2026
Processing time: 202 Days and 12.7 Hours
Core Tip
Core Tip: Post-stroke seizures require pathways that combine risk stratification, timely therapy, and neuropsychiatric care. We synthesize consistent predictors and translate them into a five-step framework usable in the emergency department, stroke unit, and early follow-up. The approach endorses the use of validated tools, targeted early electroencephalography, correction of precipitants, individualized non-enzyme-inducing antiseizure therapy when indicated, and brief screening for mood and cognition with structured referral. Standardized discharge bundles and pragmatic follow-up are emphasized. Routine primary prophylaxis is discouraged.