Yu W, Wang F. Analysis of emergency adolescent antidepressant poisoning incidence and family psychological environment influencing factors. World J Psychiatry 2026; 16(4): 115520 [DOI: 10.5498/wjp.v16.i4.115520]
Corresponding Author of This Article
Fang Wang, Department of Emergency Medicine, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, No. 261 Huansha Road, Shangcheng District, Hangzhou 310006, Zhejiang Province, China. i289412281@163.com
Research Domain of This Article
Psychology, Clinical
Article-Type of This Article
Retrospective Study
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Apr 19, 2026 (publication date) through Mar 30, 2026
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Journal Information of This Article
Publication Name
World Journal of Psychiatry
ISSN
2220-3206
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Yu W, Wang F. Analysis of emergency adolescent antidepressant poisoning incidence and family psychological environment influencing factors. World J Psychiatry 2026; 16(4): 115520 [DOI: 10.5498/wjp.v16.i4.115520]
World J Psychiatry. Apr 19, 2026; 16(4): 115520 Published online Apr 19, 2026. doi: 10.5498/wjp.v16.i4.115520
Analysis of emergency adolescent antidepressant poisoning incidence and family psychological environment influencing factors
Wei Yu, Fang Wang
Wei Yu, Fang Wang, Department of Emergency Medicine, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou 310006, Zhejiang Province, China
Author contributions: Yu W and Wang F conceived and designed the study; Yu W collected the clinical data, conducted the statistical analyses, and drafted the initial manuscript; Wang F supervised the study, provided critical revisions, and approved the final manuscript. Both authors have read and agreed to the published version of the manuscript and are accountable for all aspects of the work.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of the Hangzhou First People’s Hospita (Approval No. 2025ZN372-1) and conducted in accordance with the Declaration of Helsinki.
Informed consent statement: The requirement for informed consent was waived by the Institutional Review Board of the Hangzhou First People’s Hospital because the study used de-identified retrospective data and involved no direct patient contact.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: De-identified data supporting the findings of this study are available from the corresponding author upon reasonable request and with institutional permission.
Corresponding author: Fang Wang, Department of Emergency Medicine, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, No. 261 Huansha Road, Shangcheng District, Hangzhou 310006, Zhejiang Province, China. i289412281@163.com
Received: November 7, 2025 Revised: December 8, 2025 Accepted: January 20, 2026 Published online: April 19, 2026 Processing time: 142 Days and 18.9 Hours
Core Tip
Core Tip: Among adolescents presenting to the emergency department, antidepressant poisoning comprised 11.2% of visits and was predominantly intentional. Multivariable analysis showed higher depressive symptoms (Center for Epidemiologic Studies Depression Scale), greater parental psychological distress (Symptom Checklist-90), lower social support (Social Support Rating Scale), and unstable family structure (Family Structure Characteristics Questionnaire) independently correlated with antidepressant poisoning, especially in females. These findings support a family-centered, bio-psycho-social prevention strategy that couples rapid emergency department screening with targeted interventions for parental mental health and adolescent social-support strengthening.
