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Letter to the Editor
Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Feb 19, 2026; 16(2): 114478
Published online Feb 19, 2026. doi: 10.5498/wjp.v16.i2.114478
Cognitive signatures of conditional reasoning dysfunction in major depression
Elif Yöyen
Elif Yöyen, Department of Psychology, Faculty of Humanities and Social Sciences, Sakarya University, Sakarya 54050, Türkiye
Author contributions: Yöyen E was responsible for conceptualization, methodology, investigation, resources, writing—original draft preparation, writing—review and editing, visualization, supervision.
Conflict-of-interest statement: The author declares no competing interests.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Elif Yöyen, PhD, Department of Psychology, Faculty of Humanities and Social Sciences, Sakarya University, Esentepe, No. 2 Ring Road, Sakarya 54050, Türkiye. elifyoyen@sakarya.edu.tr
Received: September 22, 2025
Revised: October 22, 2025
Accepted: November 19, 2025
Published online: February 19, 2026
Processing time: 132 Days and 10.6 Hours
Core Tip

Core Tip: Major depressive disorder (MDD) is one of the most pressing global mental health challenges, affecting hundreds of millions of individuals across all cultures and socioeconomic strata. While the affective and motivational dimensions of depression have long been emphasized, the cognitive dimension of the disorder has increasingly attracted attention. Within this cognitive framework, the study by Li et al represents an important milestone. Li et al’s investigation marks a significant step in unpacking the cognitive signatures of depression. By illuminating the electrophysiological correlates of conditional reasoning deficits, it moves beyond documenting behavioral inefficiency to uncovering the neural mechanisms that underlie impaired cognition in MDD. This line of research has the potential not only to refine our theoretical understanding of depression but also to inspire novel, targeted interventions.