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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Feb 19, 2026; 16(2): 111799
Published online Feb 19, 2026. doi: 10.5498/wjp.v16.i2.111799
Published online Feb 19, 2026. doi: 10.5498/wjp.v16.i2.111799
Correlation of frontal lobe electroencephalogram asymmetry and cognitive prognosis in schizophrenia
Shuang Sang, Department of Psychiatry, Ningbo Psychiatric Hospital, Ningbo 315032, Zhejiang Province, China
Fei Wang, Department of Medical Technology, Ningbo Psychiatric Hospital, Ningbo 315032, Zhejiang Province, China
Author contributions: Sang S designed the experiments, conducted clinical data collection, performed postoperative follow-up and recorded the data, conducted the collation and statistical analysis; Wang F make critical revisions to important knowledge content; both authors read and approved the final manuscript.
Institutional review board statement: This study was approved by the Ethics Committee of Ningbo Psychiatric Hospital, No. 2023-12.
Informed consent statement: The ethics committee agreed to waive informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All data generated or analyzed during this study are included in this published article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fei Wang, Department of Medical Technology, Ningbo Psychiatric Hospital, No. 11 Rixing House, Tongjia Village, Zhuangqiao Street, Jiangbei District, Ningbo 315032, Zhejiang Province, China. 15990586970@163.com
Received: July 11, 2025
Revised: August 7, 2025
Accepted: October 17, 2025
Published online: February 19, 2026
Processing time: 203 Days and 21.1 Hours
Revised: August 7, 2025
Accepted: October 17, 2025
Published online: February 19, 2026
Processing time: 203 Days and 21.1 Hours
Core Tip
Core Tip: This study investigates the correlation between frontal lobe electroencephalogram asymmetry and cognitive prognosis in patients with schizophrenia. By focusing on frontal alpha asymmetry and frontoparietal network connectivity, we explore novel neurophysiological biomarkers for predicting cognitive outcomes. Our findings suggest that frontal alpha asymmetry under eyes-open conditions may serve as a critical indicator of cognitive recovery post-treatment. These insights could enhance personalized treatment plans and improve prognostic evaluations in clinical settings.