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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Dec 19, 2025; 15(12): 110858
Published online Dec 19, 2025. doi: 10.5498/wjp.v15.i12.110858
Published online Dec 19, 2025. doi: 10.5498/wjp.v15.i12.110858
Stress response, complications, and postoperative recovery in patients with hepatocellular carcinoma and comorbid anxiety/depression undergoing ultrasound-guided intervention
Shuang Xu, Liu-Wei Hao, Xia Li, Xiao-Ning Zhou, Department of Medical Imaging, Henan Provincial People’s Hospital, Zhengzhou 450000, Henan Province, China
Author contributions: Xu S performed the research and drafted the manuscript; Hao LW, Li X, and Zhou XN analyzed the data; Xu S conceived the research and provided guidance; all authors reviewed and approved the final manuscript submitted for publication.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of Henan Provincial People’s Hospital (Approval No. AF/SC-08/05.0).
Clinical trial registration statement: The study was registered at the Clinical Trial Center (www.researchregistry.com) with registration number: Researchregistry11454.
Informed consent statement: All study participants and their legal guardians provided written informed consent before recruitment.
Conflict-of-interest statement: The authors declare no conflicts of interest to declare.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shuang Xu, MD, Department of Medical imaging, Henan Provincial People's Hospital, No. 7 Weiwu Road, Zhengzhou 450000, Henan Province, China.
Received: July 11, 2025
Revised: August 14, 2025
Accepted: September 23, 2025
Published online: December 19, 2025
Processing time: 139 Days and 0.6 Hours
Revised: August 14, 2025
Accepted: September 23, 2025
Published online: December 19, 2025
Processing time: 139 Days and 0.6 Hours
Core Tip
Core Tip: Compared with conventional laparoscopic hepatectomy, ultrasound-guided interventional surgery for small hepatocellular carcinoma effectively improved negative emotions (according to the Hamilton Depression and Anxiety Scales), reduced stress-response markers (e.g., C-reactive protein and vascular endothelial growth factor), decreased complication rates, promoted postoperative recovery, and enhanced quality of life.