Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Nov 19, 2025; 15(11): 107832
Published online Nov 19, 2025. doi: 10.5498/wjp.v15.i11.107832
Published online Nov 19, 2025. doi: 10.5498/wjp.v15.i11.107832
Ignoring atypical symptoms of depression in common scales
Evgeny D Kasyanov, Yana V Yakovleva, Egor S Shchepkin, Department of Social Neuro
Galina E Mazo, Deputy Director for Innovative Scientific and Innovative Development, V. M. Bekhterev National Medical Research Center for Psychiatry and Neurology, Saint Petersburg 190000, Sankt-Peterburg, Russia
Author contributions: Kasyanov ED designed the review framework and identified the research focus and analyzed the data and drafted the manuscript; Yakovleva YV and Shchepkin ES conducted the literature search and selected relevant studies; Kasyanov ED and Mazo GE conducted a data synthesis; Mazo GE provided critical revisions and final approval of the manuscript; and all the authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Evgeny D Kasyanov, MD, PhD, Department of Social Neuropsychiatry, V. M. Bekhterev National Medical Research Center for Psychiatry and Neurology, Bekhtereva St., 3, 192019, Saint Petersburg 19000, Sankt-Peterburg, Russia. i@kasyan.ru
Received: April 1, 2025
Revised: May 28, 2025
Accepted: September 10, 2025
Published online: November 19, 2025
Processing time: 219 Days and 12.1 Hours
Revised: May 28, 2025
Accepted: September 10, 2025
Published online: November 19, 2025
Processing time: 219 Days and 12.1 Hours
Core Tip
Core Tip: Common depression rating scales do not fully address atypical symptoms (e.g., mood reactivity, hypersomnia, hyperphagia, leaden paralysis, and interpersonal sensitivity), potentially underestimating atypical depression severity. Only three scales cover all five atypical features, with the Inventory of Depressive Symptomatology offering the most comprehensive assessment. Incorporating atypical symptoms is crucial for accurate severity evaluation and advancing both clinical and basic research on depression.