Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Oct 19, 2025; 15(10): 111039
Published online Oct 19, 2025. doi: 10.5498/wjp.v15.i10.111039
Published online Oct 19, 2025. doi: 10.5498/wjp.v15.i10.111039
Post-percutaneous coronary intervention psychological disorders predict poor adherence and cardiovascular events in elderly heart failure patients
Chao-Sheng Du, Ben-Chuan Hao, Shuai Mao, Zhao Yin, Shan-Shan Chen, Bei Zhao, Hui-Hui Xia, Department of Cardiology, The Ninth Medical Center, Chinese PLA General Hospital, Beijing 100101, China
Co-first authors: Chao-Sheng Du and Ben-Chuan Hao.
Co-corresponding authors: Bei Zhao and Hui-Hui Xia.
Author contributions: Du CS and Hao BC designed the research study; Mao S and Yin Z collected and organized the clinical data; Xia HH and Zhao B performed the statistical analysis and interpreted the results; all authors reviewed and approved the final version of the manuscript. Du CS and Hao BC drafted the manuscript, and contributed equally to this work as co-first authors. We have designated both Author Zhao B and Xia HH as co-corresponding authors because they contributed equally but in different capacities to the success of the study. Specifically, Xia HH was responsible for the study concept, protocol design, and supervision of data analysis. Zhao B oversaw patient recruitment, data collection, and played a leading role in manuscript drafting and revision. Both authors have full access to the data and agree to take joint responsibility for the integrity of the work. Given their complementary roles and equal contributions, we believe it is appropriate to list them as co-corresponding authors.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the Strategic Support Force Characteristic Medical Center of the Chinese People’s Liberation Army (Approval No. LL-LCSY-2023-05).
Informed consent statement: Due to the retrospective design and use of anonymized clinical data, the requirement for signed informed consent was waived by the ethics committee.
Conflict-of-interest statement: The authors declare that there is no conflict of interest related to this study.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Hui Xia, Department of Cardiology, The Ninth Medical Center, Chinese PLA General Hospital, No. 9 Anxiang Beili, Chaoyang District, Beijing 100101, China. xhh.0607@163.com
Received: July 11, 2025
Revised: August 12, 2025
Accepted: August 22, 2025
Published online: October 19, 2025
Processing time: 77 Days and 0.1 Hours
Revised: August 12, 2025
Accepted: August 22, 2025
Published online: October 19, 2025
Processing time: 77 Days and 0.1 Hours
Core Tip
Core Tip: This retrospective study highlights the high prevalence (40%) of psychological disorders within 6 months after percutaneous coronary intervention (PCI) in elderly heart failure patients. These disorders-particularly depression and anxiety-were significantly associated with poor medication adherence, as measured by the 8-item Morisky Medication Adherence Scale. Moreover, both psychological morbidity and low adherence independently predicted major adverse cardiovascular events during 2-year follow-up. The findings support routine psychological screening and adherence-focused interventions as essential components of post-PCI management in older adults to reduce long-term cardiovascular risk.