Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Oct 19, 2025; 15(10): 110719
Published online Oct 19, 2025. doi: 10.5498/wjp.v15.i10.110719
Published online Oct 19, 2025. doi: 10.5498/wjp.v15.i10.110719
Methodological reflections on a nutritional status-based nomogram for predicting cognitive impairment in elderly hypertensive patients
Abdul Rauf Khalid, Medical Officer, Bahria International Hospital Orchard, Lahore 54000, Pun jab, Pakistan
Abdulqadir J Nashwan, Department of Nursing, Hamad Medical Corporation, Doha 3050, Qatar
Author contributions: Khalid AR wrote the original draft; Nashwan AJ critically reviewed the manuscript; All authors have read and approved the final version.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Abdulqadir J Nashwan, MSc, Researcher, Department of Nursing, Hamad Medical Corporation, Al Rayyan Road, Doha 3050, Qatar. anashwan@hamad.qa
Received: June 13, 2025
Revised: June 25, 2025
Accepted: July 29, 2025
Published online: October 19, 2025
Processing time: 105 Days and 20.6 Hours
Revised: June 25, 2025
Accepted: July 29, 2025
Published online: October 19, 2025
Processing time: 105 Days and 20.6 Hours
Core Tip
Core Tip: This critique highlights key methodological limitations in Xu et al’s predictive model for cognitive impairment in elderly hypertensive patients. Chief concerns include the small validation sample, potential reverse causality due to the cross-sectional design, insufficient discussion of alkaline phosphatase as a biomarker, omission of key cogni